About the Tumor Microenvironment Program

The Tumor Microenvironment (TME) Program is a new research program that incorporates members of the former Women's Cancer Program and some members of the Genetic Mechanisms of Cancer Program. The program consists of 34 members, representing the University of Minnesota's medical school, Institute of Engineering and Medicine (IEM), Center for Magnetic Resonance Research (CMRR), College of Veterinary Medicine, and School of Dentistry; the Minneapolis Veterans Affairs Medical Center (VAMC); and the Hormel Institute.

TME program members seek to define critical molecular and cellular mechanisms through which alterations in the tumor microenvironment contribute to tumor-related factors in malignant progression. The program is organized in three distinct but overlapping themes that have the potential to impact tumor progression in several ways, including reducing tumor burden, limiting metastasis, and lessening cancer-induced pain, all of which affect morbidity and mortality in cancer patients.

Research themes

  • Mechanisms of cancer-associated pain
  • Critical cellular interactions in the tumor microenvironment that facilitate malignant progression
  • Key molecular interactions critical in invasion and therapeutic resistance

Tumor Microenvironment program meetings

Held the third Tuesday of each month
3-150 Cancer & Cardiovascular Building

Program leaders

Kalpna Gupta

Kalpna Gupta, PhD

James McCarthy

James McCarthy, PhD

Meet our research program members