American Cancer Society Institutional Research Grant

Objective

The purpose of the American Cancer Society’s Institutional Research Grant (ACS-IRG) is to support the initiation of promising new cancer-related research projects by junior faculty members (Assistant Professors or their equivalents), so they can obtain preliminary results that will enable them to compete successfully for national research grants. IRGs are intended to support independent, self-directed investigators early in their careers, for whom the institution must provide research facilities or space customary for an independent investigator. Applicants for the individual awards should be within six years of their first independent research or faculty appointment. This funding mechanism is not to provide supplemental research support but it can be used as bridge funding for faculty members who have been PI on research grant(s) from major national funding agencies. Cancer-related research includes but is not restricted to genetic mechanisms of cancer, molecular mechanisms of cancer progression and metastasis, development of novel cancer therapeutic models and translational research, transplantation, cancer immunology, and immunotherapies.

Grant Program Contacts

All questions related to the application process, requirements, or eligibility should be directed to:
Jessica Raines-Jones
Research Development Coordinator
612-624-8679
mccgrant@umn.edu

Any questions regarding the applicability of research should be directed to:
Kaylee Schwertfeger, PhD
schwe251@umn.edu

Previous Grantees

2018

Alpha-defensin 5 single nucleotide polymorphism rs4416345 and dysbiosis in allogeneic hematopoietic cell transplantation
Armin Rashidi, MD, PhD, Department of Medicine, Medical School

2016-2017

2016

The Lyna Signaling Pathway in Tumor-Associated Macrophages
Tanya Freedman, PhD, Department of Pharmacology, Medical School

Risk Factors of 'Chemo Brain' among Women Treated for Ovarian Cancer
Rachel Vogel, PhD, Department of Obstetrics, Gynecology and Women’s Health, Medical School

Assessing the effect of Glucobrassicin-rich Brussels Sprouts on the Metabolism of Deuterated Phenanthrene in Current and Former Cigarette Smokers
Naomi Fujioka, MD, Department of Medicine, Medical School

A Microbiome-based Diagnostic for Colorectal Cancer
Ran Blekhman, PhD, Department of Genetics, Cell Biology and Development, Medical School

2017

Biomaterial platform for predicting clinical outcome in ovarian cancer
Samira Azarin, PhD, Department of Chemical Engineering and Materials Sciences, College of Science and Engineering
 
The brain bystander consequences of non-brain radiation therapy in solid tumors
Davis Seelig, PhD, DVM, Veterinary Clinical Sciences, College of Veterinary Medicine
 
Employing CD4+ T cells for immunotherapy of epithelial malignancies
Ingunn Stromnes, PhD, Center for Immunology, Medical School
 
Targeted therapy for leukemia in the central nervous system
Peter Gordon, MD, PhD, Pediatric Hematology/Oncology, Medical School

2014-2015

2014

PELP1 Protein Interactions that Promote Early Mammary Carcinogenesis
Julie Ostrander, PhD, Department of Medicine, Medical School

Understanding the Effects of Prostate Cancer on Caregivers for Gay and Bisexual Men
Benjamin D. Capistrant, ScD, Division of Epidemiology & Community Health, School of Public Health

Defining the Role of MICA in Pancreatic Cancer
Anna Prizment, PhD, Division of Epidemiology & Community Health, School of Public Health

The Role of the Immune System in Development of Cardiometabolic Syndrome among Survivors of Hematopoietic Cell Transplantation
Lucie Turcotte, MD, MPH, Department of Pediatrics, Medical School

2015

AMACR Promoter Driven Reporter Genes for Prostate Cancer Imaging
Aaron M. LeBeau, PhD, Department of Pharmacology, Medical School

Decoding the Cellular Mechano-some at a Molecular Level using Novel Fluorescent Molecular Tension Sensors
Wendy Gordon, PhD, Department of Biochemistry, Molecular Biology and Biophysics, Medical School

DNA Adductomics for the Investigation of Alcohol Related DNA-damage
Silvia Balbo, PhD, Division of Environmental Health Sciences, School of Public Health

Cell Cycle Control in Latent Breast Preneoplastic Cells
Cheuk T. Leung, PhD, Department of Pharmacology, Medical School

 

2012-2013

2012

Role of Tumor Suppressor CHD5 in DNA Damage Repair
Anindya Bagchi, PhD, Genetics, Cell Biology and Development, Medical School

Tunneling Nanotubes as a Mechanism for Intercellular Transfer of microRNAs and Cellular Contents in Colon Cancer
Emil Lou, MD, PhD, Department of Medicine, Medical School

Translational Regulation of p53 Induction in Response to Cellular Stress
Da-Qing Yang, PhD, Section of Nutrition and Metabolism, Hormel Institute

Targeting PTEN/AKT to Downregulate P-gp and BCRP for Improved Glioblastoma Therapy
Bjoern Bauer, PhD, Department of Pharmacy Practice and Pharmaceutical Sciences, College of Pharmacy

Phase II Pilot Study to Assess LMI Vaccine with Ipilimumab
Gautam Jha, MBBS, MS, Department of Medicine, Medical School

Development of Novel p16INK4a Mimetics as Anticancer Therapy
Mark Klein, MD, Department of Medicine, Medical School

2013

RAS Signaling Pathways in the Maintenance of Acute Myeloid Leukemia Stem Cells
Zohar Sachs, PhD, Department of Medicine, Medical School

The Dual Role of microRNA-206 in Preventing Both Non-alcoholic Fatty Liver Disease and the Development of Hepatocellular Carcinoma
Guisheng Song, PhD, Department of Medicine, Medical School

Towards Global Characterization of Proline Hydroxylome in Response to Hypoxia
Yue Chen, PhD, Biochemistry, Molecular Biology, and Biophysics, Medical School

PELP1 Protein Interactions that Promote Early Mammary Carcinogenesis
Julie Ostrander, PhD, Department of Medicine, Medical School

Polarity Switching Peptides for CREB:KIX Inhibition
William Pomerantz, PhD, Department of Chemistry, College of Science and Engineering

2010-2011

2010

Deep Penetrating Delivery of siRNA-loaded Nonogels to Ovarian Tumors
Erin Dickerson, PhD, Department of Veterinary Clinical Sciences, College of Veterinary Medicine

2011

Identifying Tumor Endothelial Cell Antigen Presentation.
Ruud P. Dings, PhD, Department of Biochemistry, Molecular Biology and Biophysics, Medical School

Targeting Cancer Stem Cells with Parthenolide-functionalized Gold Nanoparticles
Daniel A. Harki, PhD, Department of Medicinal Chemistry, College of Pharmacy

Molecular Probes for Generic Label-free and Antibody-free Time-resolved Luminescent Kinase Screening
Valerie C. Pierre, PhD, Department of Chemistry, College of Science and Engineering

Role of mTOR in Alternative Cleavage and Polyadenylation
Jeongsik Yong, PhD, Department of Biochemistry, Molecular Biology and Biophysics, Medical School

Development of Advanced Electrical Property Imaging Techniques for Prostate Cancer Screening
Yingchun Zhang, PhD, Department of Urology, Medical School

    Contact Us: 

    Jessica Raines-Jones
    Research Development Coordinator
    612-624-8679
    mccgrant@umn.edu

    Elizabeth Fedie
    Research Development Manager
    612-624-0653
    efedie@umn.edu 

    David Largaespada, PhD
    Associate Director for Basic Sciences

    612-626-4979
    larga002@umn.edu

    Apply Here!

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