Osteosarcoma Research at the U of M
The Biology of Osteosarcoma (BOOST) Registry and Biobank offers a single location where every patient with osteosarcoma and their relatives can participate in research to better understand how genes and environment affect the development and survival of this disease.
Osteosarcoma patients diagnosed at any age are invited to enroll in BOOST, provide a DNA sample through the mail, and complete some questions about themselves. After enrolling you may invite your relatives to participate in BOOST as well.
Since we may learn about osteosarcoma by studying genes we are including relatives because we can learn a lot by comparing patient DNA to that of their relatives. We also with your permission will track any future cancers in you and your family by linking to cancer registries.
The ultimate goal of BOOST is to explain how children and adults develop osteosarcoma so we can predict its occurrence, catch it early and someday prevent it from occurring at all.
It is difficult to make progress in a rare disease unless patients participate as much as possible. Scientists can only tell what genes are important to disease and survival if you have large number of patients.
Currently, very few adult patients with osteosarcoma cases participate in studies and only half of the pediatric patients participate. Through the power of the web, BOOST is the place where patients can participate in research no matter where they are.
The ultimate goal of BOOST is to explain how children and adults develop osteosarcoma so we can predict its occurrence, catch it early and someday prevent it from occurring at all. In addition, BOOST will allow us to determine what the gene influences on survival and treatment-related side effects.