What is the GO Study?

The GO (Genetics of Osteosarcoma) Study was designed to try to find causes of osteosarcoma in children. The main purpose of this study is to understand how genes might affect young people's chances of developing osteosarcoma. To do this we will compare the genes of young people with osteosarcoma to the genes of their parents. We will also look at how some lifestyle factors work with genes in osteosarcoma. Lastly, we will use medical records to see if young people with osteosarcoma grow differently than other young people.

(For more detailed participant information, please click on "Information for GO Study Participants" links on the right side of this page.)

Who is eligible for this study?

Families are eligible for this study if:

1. the child was diagnosed with osteosarcoma after 12/24/2007.
2. the child was diagnosed with osteosarcoma at less than 20 years of age.
3. at least one biological parent is alive and willing to participate.
4. the parents and child filling out the questionnaires understand English or Spanish.
5. a child is registered with the Children's Oncology Group.

Parents of children who were diagnosed with osteosarcoma, but are deceased, may be eligible to participate.

How does the study work?

If you participate, we will ask for three things:

• we would collect some cheek cells from you and your child to look at your DNA,
• we would ask you and your child to fill out surveys, and
• we would collect medical records from your child's doctors to see how he or she grew.

We can use cheek cells from one of your other children (if you have one) if one parent cannot participate.

How can I participate?

Contact our research coordinator, Amanda Kabage at
1-877-210-9550 or kaba0012@umn.edu.

Sponsor

National Institutes of Health/National Cancer Institute

Researcher in charge of the study

Logan G. Spector, Ph.D.
University of Minnesota Division of Epidemiology/Clinical Research
Department of Pediatrics
420 Delaware St. SE MMC 715
Minneapolis, MN 55455

Questions?

Please read the following Information for GO Study Participants question-and-answer pages:

• For parents of children who have been diagnosed with osteosarcoma
• For children who have been diagnosed with osteosarcoma
• For siblings of children who have been diagnosed with osteosarcoma
• Why is this study being done?

Or call the study staff at the University of Minnesota at 1-877-210-9550.