Program: Cancer Detection, Treatment and Survivorship Research
Professor, Department of Surgery
Chief, Division of Surgical Oncology
Owen H. and Sarah Wangensteen Chair in Experimental Surgery

tuttl006@umn.edu
612-625-2991 — office
Preferred method of contact: Phone my assistant Tina Russell at 612-625-2991 or e-mail me directly

• M.D.: Johns Hopkins University School of Medicine, 1990
• Residency: The Medical College of Virginia, 1994
• Fellowship: M.D. Anderson Cancer Center, 1996

Dr. Tuttle's clinical profile
(University of Minnesota Physicians Web site)

Research Interests

• Hyperthermic Intraperitoneal Chemotherapy
• Radiofrequency Ablation of Breast Cancer
• Partial Breast Radiation

Active Clinical Research Protocols:

1. ACOSOG Z0011 (local PI)
2. Sunbelt Melanoma Trial (local PI)
3. Hyperthermic Intraoperative Peritoneal Chemotherapy for Gastrointestinal Malignancies (PI) Brachytherapy for Ductal Carcinoma in Situ (PI)
4. Sentinel Lymph Node Biopsy Before Preoperative Chemotherapy: Factors Predicting Non-Sentinel Lymph Node Metastases (PI)
5. Laparoscopic Hyperthermic Peritoneal Perfusion for Malignant Ascites (PI)
6. ACOSOG Z9031 (local PI)
7. MRI assessment of Tumor Necrosis After Radiofrequency Ablation for Breast Cancer (PI)

Selected Publications

Virnig BA, Tuttle TM. Random physician effect and comparative effectiveness of treatment for ductal carcinoma in situ. J Natl Cancer Inst. 2011;103:81-82.

Groth SS, Virnig BA, Al-Refaie WB, Jarosek SL, Jensen EH, Tuttle TM. Appendiceal carcinoid tumors: Predictors of lymph node metastasis and the impact of right hemicolectomy on survival. J Surg Oncol. 2011;103:39-45.

Dudeja V, Habermann EB, Zhong W, Tuttle TM, Vickers SM, Jensen EH, Al-Refaie WB. Guideline recommended gastric cancer care in the elderly: insights into the applicability of cancer trials to real world. Ann Surg Oncol. 2011;18:26-33.

Parsons HM, Habermann EB, Tuttle TM, Al-Refaie WB. Conditional survival of extremity soft-tissue sarcoma: results beyond the staging system. Cancer 2010 [Epub ahead of print].

Kane RL, Virnig BA, Shamliyan T, Wang SY, Tuttle TM, Wilt TJ. The impact of surgery, radiation, and systemic treatment on Detection in patients with ductal carcinoma in situ. J Natl Cancer Inst Monogr. 2010; 2010(41):130-133.

Shamliyan T, Wang SY, Virnig BA, Tuttle TM, Kane RL. Association between patient and tumor characteristics with clinical Detection in women with ductal carcinoma in situ. J Natl Cancer Inst Monogr. 2010;2010(41):121-129.

Tuttle TM, Shamliyan T, Virnig BA, Kane RL. The impact of sentinel lymph node biopsy and magnetic resonance imaging on important Detection among patients with ductal carcinoma in situ. J Natl Cancer Inst Monogr. 2010;2010(41):117-120.

Virnig BA, Wang SY, Shamilyan T, Kane RL, Tuttle TM. Ductal carcinoma in situ: risk factors and impact of screening. J Natl Cancer Inst Monogr. 2010;2010(41):113-116.

Boughey JC, Mittendorf EA, Solin LJ, Michael Dixon J, Tuttle TM, Beitsch PD, Cody HS, Leitch AM, Newman LA. Controversies in breast surgery. Ann Surg Oncol. 2010;17(Suppl 3):230-232.

Tuttle TM, Habermann EB, Virnig B. Re: Population-based study of contralateral prophylactic mastectomy and survival Detection of breast cancer patients. J Natl Cancer Inst. 2010;102(:1371-2; author reply 1372-1373.

Rueth NM, Murray SE, Huddleston SJ, Abbott AM, Greeno EW, Kirstein MN, Tuttle TM. Severe electrolyte disturbances after hyperthermic intraperitoneal chemotherapy: oxaliplatin versus mitomycin C. Ann Surg Oncol. 2011;18:174-180.

Habermann EB, Abbott A, Parsons HM, Virnig BA, Al-Refaie WB, Tuttle TM. Are mastectomy rates really increasing in the United States? J Clin Oncol. 2010;28:3437-441.

Tuttle TM, Abbott A, Arrington A, Rueth N. The increasing use of prophylactic mastectomy in the prevention of breast cancer. Curr Oncol Rep. 2010;12:16-21.

Al-Refaie WB, Habermann EB, Dudeja V, Vickers SM, Tuttle TM, Jensen EH, Virnig BA. Extremity soft tissue sarcoma care in the elderly: insights into the generalizability of NCI Cancer Trials. Ann Surg Oncol. 2010;17:1732-1738.

Al-Refaie WB, Parsons HM, Henderson WG, Jensen EH, Tuttle TM, Rothenberger DA, Kellogg TA, Virnig BA. Body mass index and major cancer surgery Detection: lack of association or need for alternative measurements of obesity? Ann Surg Oncol. 2010;17:2264-2273.

Al-Refaie WB, Habermann EB, Jensen EH, Tuttle TM, Pisters PW, Virnig BA. Surgery alone is adequate treatment for early stage soft tissue sarcoma of the extremity. Br J Surg. 2010;97:707-713.

Rueth NM, Groth SS, Tuttle TM, Virnig BA, Al-Refaie WB, Habermann EB. Conditional survival after surgical treatment of melanoma: an analysis of the Surveillance, Epidemiology, and End Results database. Ann Surg Oncol. 2010;17):1662-1668.

Virnig BA, Tuttle TM, Shamliyan T, Kane RL. Ductal carcinoma in situ of the breast: a systematic review of incidence, treatment, and Detection. J Natl Cancer Inst. 2010;102:170-178.

Borja-Cacho D, Al-Refaie WB, Vickers SM, Tuttle TM, Jensen EH. Laparoscopic distal pancreatectomy. J Am Coll Surg. 2009;209:758-765.

Virnig BA, Shamliyan T, Tuttle TM, Kane RL, Wilt TJ. Diagnosis and management of ductal carcinoma in situ (DCIS). Evid Rep Technol Assess (Full Rep). 2009;(185):1-549.