Research Program: Transplant Biology & Therapy
Associate Professor, Department of Pediatrics, Division of Hematology, Oncology and Blood and Marrow Transplant, and
Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine
Director, Cytokine Reference Laboratory
Director of Graduate Studies, Clinical Laboratory Sciences

panos001@umn.edu
612-626-1926 — office
Preferred method of contact: e-mail

Dr. Panoskaltsis-Mortari received her Ph.D. from the University of Western Ontario. She was a postdoctoral fellow in the Department of Pathology at the University of Alabama and a postdoctoral research associate in the Department of Pediatrics at the University of Minnesota. She joined the University of Minnesota faculty in 1995.

Dr. Panoskaltsis-Mortari has board certification from the American Board of Medical Laboratory Immunology. She is a member of numerous immunology, pulmonary, and hematology professional societies, and the author of more than 130 articles, which have appeared in such publications as Journal of Experimental Medicine, Journal of Clinical Investigation, Blood, Biology of Blood and Marrow Transplantation, American Journal of Physiology (Lung, Cell. & Mol. Physiol.), and Journal of Immunology.

Research Interests

Dr. Panoskaltsis-Mortari's laboratory research focuses on the study of bone-marrow transplant-related lung injury (idiopathic pneumonia syndrome) and the biology of graft-versus-host disease, both of which are major complications causing morbidity and mortality post-BMT. She is also exploring novel methods of enhancing lung repair after transplant using growth factors and multipotential adult stem cells.

Selected Publications

Panoskaltsis-Mortari A, Tram K, Price A, Wendt C, Blazar BR. A new murine model for obliterative bronchiolitis post-bone marrow transplant. American Journal of Respiratory and Critical Care Medicine, Epub June 15, 2007.

Kharbanda S, Panoskaltsis-Mortari A, Haddad IY, Blazar BR, Orchard PJ, Cornfield DN, Grewal SS, Peters C, Regelmann WE, Milla CE, Baker KS. Inflammatory cytokines and the development of pulmonary complications after allogeneic hematopoietic cell transplantation in patients with inherited metabolic storage disorders. Biol Blood Marrow Transplant. 2006; 12:430-437.

Miller JS, Curtsinger J, Berthold M, Malvey K, Bliss RL, Le CT, Fautsch SK, Dudek AZ, Blazar BR, Panoskaltsis-Mortari A. Diminished neo-antigen response to keyhole limpet hemocyanin (KLH) vaccines in patients after treatment with chemotherapy or hematopoietic cell transplantation. Clin. Immunol. 2005;117:144-151.

Wysocki CA, Panoskaltsis-Mortari A, Blazar BR, Serody JS. Leukocyte migration and graft-versus-host disease. Blood 2005;105:4191-4199.

Panoskaltsis-Mortari A, Price A, Hermanson JR, Taras E, Lees C, Serody J, Blazar BR. (2004). In vivo imaging of graft-versus-host-disease (GVHD) in mice. Blood 103:3590-3598.