Research Program: Women's Cancer
Associate Professor, Department of Mechanical Engineering

hubel001@umn.edu
612-626-4451 — office
612-626-4466 — lab
Preferred method of contact: e-mail

Dr. Hubel is Mayhugh Associate Professor of Mechanical Engineering and previously held a faculty position in the Department of Laboratory Medicine and Pathology at the University of Minnesota. For more than 15 years, Dr. Hubel has studied both basic science and translational issue behind cell and tissue preservation (liquid storage and cryopreservation). Her research focuses on cell and tissue preservation for human therapeutic applications. She has published numerous articles related to cell and tissue preservation and two patents related to cell preservation technology. Prof. Hubel has been an active member in the Society for Cryobiology and a member the International Society for Cellular Therapy.

Research Interests

Preservation of cellular therapies and nanotechnology for the detection of cancer.

Selected Publications

Fleming KK, Longmire EA, Hubel A. "Characterization of diffusion-based extraction in cell-laden flow through a microfludic device", J Biomech Engr, 129: 703-711, 2007.

Chang A, Dantzig J, Darr TB, Hubel A. "Modeling the interaction of biological cells with a solidifying interface," J Computational Phys, 226: 1808-1827, 2007.

Hubel A, Darr TB, Chang A, Dantzig J. "Cell partitioning during the directional solidification of trehalose solutions," Cryobiology, 55: 182-188, 2007.

Fleming K, Hubel A. "Cryopreservation of hematopoietic stem cells: emerging science, technology and issues," Trans Med Hemother, 34: 268-275, 2007.

Fleming, KK and Hubel, A, "Cryopreservation of hematopoietic and non-hematopoietic cells", Transf. Apheresis Sci., 34: 309-315, 2006.

Balasubramanian SK, Bischof JC, and Hubel A. "Water transport and IIF parameters for a connective tissue equivalent," Cryobiology, 52: 62-73, 2006.

Hubel A and Waxberg M. "Preservation of Cell-based Products for Human Therapeutic Application", Regulatory Affairs Focus, 36-37, February 2006.