Research Program: Prevention & Etiology
Assistant Professor, Division of Epidemiology and Community Health

flood009@umn.edu
612-624-2891 — office

Dr. Flood received an undergraduate degree in biology from Princeton University and a master's degree in history from the University of New Hampshire. He finished his Ph.D. in the Division of Nutritional Sciences at Cornell University and then completed postdoctoral training in the Division of Cancer Epidemiology and Genetics at the National Cancer Institute. Dr. Flood joined the faculty at the University of Minnesota in 2003.

Research Interests

Dietary causes of cancer with primary emphasis on colorectal cancer. Particularly interested in the role of insulin resistance, the IGF axis, and related factors such as glycemic load and obesity in the etiology of colorectal cancer.

Selected Publications

Flood A., E.M. Velie, R. Sinha, J.V. Lacey, Jr., C. Schairer, A. Schatzkin. "Meat, dietary fat, and risk of colorectal cancer in the Breast Cancer Detection Demonstration Project." American Journal of Epidemiology. Volume 158, No. 1, July 1, 2003, pp. 59-68.

Woodson, K., A. Flood, L. Green, J.A. Tangrea, J. Hanson, B. Cash, A. Schatzkin, P. Schoenfeld. "Loss of IGF2 Imprinting and the Presence of Screen Detected Colorectal Adenomas in Women." Journal of the National Cancer Institute, Volume 96, No. 5, March 3, 2004, pp. 407-410.

Peters, U., N. Chatterjee, K. McGlynn, R.E. Schoen, T.R. Church, R.S. Bresalier, M. Gaudet, A. Flood, A. Schatzkin, R.B. Hayes. "Association of Calcium Intake and Colorectal Adenoma in a U.S. Colorectal Cancer Early Detection Program." American Journal of Clinical Nutrition. Volume 80, No. 5, November 2004, pp 1358-1365.

Flood, A., U. Peters, N. Chatterjee, J.V. Lacey, Jr., C. Schairer, A. Schatzkin. "Calcium from Diet and Supplements Is Associated with Reduced Risk of Colorectal Cancer in a Prospective Cohort of Women" Cancer Epidemiology Biomarkers and Prevention. Volume 14, No. 1, January 2005, pp. 126-132.

Mai, V., A. Kant, A. Flood, J.V. Lacey, Jr., C. Schairer, A. Schatzkin. "Diet quality and subsequent cancer incidence and mortality in a prospective cohort of women." International Journal of Epidemiology. Volume 34, No. 1, January 2005, pp. 54-60.

Schoenfeld, P., B. Cash, A. Flood, R. Dobhan, J. Eastone, W. Coyle, J.W. Kikendall, H.M. Kim, D.G. Weiss, T. Emory, A. Schatzkin, D. Lieberman. "COlorectal Neoplasia screening with Colonoscopy in average-risk women at Regional Naval medical centers: The CONCeRN Study." New England Journal of Medicine. May 19, 2005, Volume 352, No. 20, May 19, 2005, pp. 2061-2068.

Velie E.M., C. Schairer, A. Flood, J.-P. He, R. Khattree, A. Schatzkin. "Empirically derived dietary patterns and risk of postmenopausal breast cancer in a large prospective cohort study." American Journal of Clinical Nutrition. Volume 82, 2005, pp 1308-1319.

Flood, A., A.F. Subar, S.G. Hull, T.P. Zimmerman, D.J.A. Jenkins, A. Schatzkin. "Methodology for adding glycemic load values to the NCI Diet History Questionnaire database." Journal of the American Dietetic Association. Volume 106, No. 3, 2006, pp 393-402.

Flood, A., U. Peters, D.J.A. Jenkins, N. Chatterjee, A. Subar, T. Church, R. Bresalier, J.L. Weissfeld, R.B. Hayes, A. Schatzkin for the PLCO Project Team. "Carbohydrate, glycemic index, and glycemic load and colorectal adenomas in the PLCO Screening Study." American Journal of Clinical Nutrition. Volume 84, 2006, 1184-1192.

Strayer, L., D.R. Jacobs, Jr., C. Schairer, A. Schatzkin, A. Flood. "Dietary Carbohydrate, Glycemic Index and Glycemic Load and the Risk of Colorectal Cancer in the BCDDP Cohort." Cancer Causes and Control. Volume 18, 2007, pp 853-663.

Flood, A., V. Mai, R. Pfeiffer, L. Kahle, A. Remaly, E. Lanza, A. Schatzkin. "Elevated serum concentrations of insulin and glucose increase risk of recurrent colorectal adenomas." Gastroenterology. Volume 133, 2007, pp 1423-1429.

Prizment, A.E., K.E. Anderson, J. Cerhan, A. Flood, J. Ross, A.R. Folsom. "History of allergy and reduced incidence of colorectal cancer, Iowa Women's Health Study." Cancer Epidemiology Biomarkers and Prevention. Volume 16, No. 11, 2007, pp. 2357-2362.

Mitrou PN, V. Kipnis, J. Reedy, A.F. Subar, A. Thiebaut, E. Wirfält, D. Midthune, A. Flood, T. Mouw, D. Campbell, A.R. Hollenbeck, M.F. Leitzmann, A. Schatzkin "Mediterranean Dietary Pattern and Prediction of All-Cause Mortality in a US Population—Results from the NIH-AARP Diet and Health Study." Archives of Internal Medicine. Volume 16, No. 22, 2007, pp. 2461-2468.

Flood, A., V. Mai, R. Pfeiffer, L. Kahle, A.T. Remaley, C.J. Rosen, E. Lanza, A. Schatzkin. "The Effects of a High-Fruit and Vegetable, High-Fiber, Low-Fat Dietary Intervention on Serum Concentrations of Insulin, Glucose, IGF-I, and IGFBP-3." European Journal of Clinical Nutrition. Volume 62, 2008, pp. 186-196.

Lim, U., A. Flood, S.W. Choi, D. Albanes, A.J. Cross, A. Schatzkin, R. Sinha, H.A. Katki, B.D. Cash, P. Schoenfeld, R. Stolzenberg-Solomon "Genomic methylation of leukocyte DNA in relation to colorectal adenoma among asymptomatic women." Gastroenterology. Volume 134, No. 1, 2008, pp. 47-55.

Reedy J., P.N. Mitrou, S.M. Krebs-Smith, E. Wirfält, A. Flood, V. Kipnis, D. Midthune, M. Leitzmann, T. Mouw, A. Hollenbeck, A. Schatzkin, A.F. Subar. "Index-based dietary patterns and risk of colorectal cancer: the NIH-AARP Diet and Health Study." American Journal of Epidemiology. Volume 168, No. 1, 2008, pp. 38-48.

Flood, A., T. Rastogi, E. Wirfält, P.N. Mitrou, J. Reedy, A.F. Subar, V. Kipnis, T. Mouw, M. Leitzmann, A. Schatzkin. "Dietary patterns as identified by factor analysis and colorectal cancer among middle aged Americans." American Journal of Clinical Nutrition. Volume 88, 2008, pp. 176-184.

Flood, A., V. Mai, R. Pfeiffer, C. Rosen, E. Lanza, A. Schatzkin. "Serum concentrations of IGF-I and IGFBP-3 and recurrent colorectal adenomas." Cancer Epidemiology Biomarkers and Prevention. Volume 17, No. 6, 2008, pp. 1493-1498.

Limburg, P.J., W. Liu-Mares, R.A. Vierkant, A.H. Wang, L. Harnack, A. Flood, T.A. Sellers, J.R. Cerhan. "Prospective evaluation of trans-fatty acid intake and colorectal cancer risk among older women." International Journal of Cancer. In press.

Wirfält, E., D. Midthune, J. Reedy, P.N. Mitrou, A.F. Subar, A. Flood, M. Leitzmann, V. Kipnis, A.R. Hollenbeck, A. Schatzkin. "Associations between food patterns defined by cluster analysis and colorectal cancer incidence in the NIH-AARP diet and health study." European Journal of Clinical Nutrition. 2008 Aug 6. [Epub ahead of print]