Research Program: Women's Cancer
Assistant Professor, Department of Radiology, Medical School

bolan@cmrr.umn.edu
612-625-6526 — office
Preferred method of contact: e-mail

Dr. Bolan is an assistant professor in the Medical School's Department of Radiology. After receiving his B.S. in mechanical engineering from the University of Illinois at Urbana-Champaign and post-graduate studies at University of California, Berkeley, Dr. Bolan spent five years working in industry as a software engineer. He joined Dr. Michael Garwood's group at the University of Minnesota in 1999 and received his Ph.D. in biomedical engineering in 2003 while developing methods for performing quantitative MR spectroscopy of breast cancer. He stayed on at the University of Minnesota's Center for Magnetic Resonance Research as a postdoctoral associate and later as an assistant professor. His research focuses on developing methods for MR imaging and spectroscopy of cancer in animal models and human subjects, and translating research methodologies into clinical practice.

Research Interests

• MR imaging and spectroscopy of breast and ovarian cancer
• MR imaging and visualization of microvasculature in animal models
• Computational methods for MR spectroscopy analysis
• Methods for abdominal high-field MR spectroscopy

Selected Publications

Bolan PJ, DelaBarre L, Baker EH, Merkle H, Everson LI, Yee D, Garwood M. Eliminating Spurious Sidebands in 1H MRS of Breast Lesions. Magn Reson Med 2002; 48:215-222

Bolan PJ, Meisamy S, Baker EH, Lin J, Emory T, Nelson M, Everson LI, Yee D, Garwood M. In vivo quantification of choline compounds in the breast with 1H MR spectroscopy. Magn Reson Med 2003; 50:1134-1143

Bolan PJ, Henry PG, Baker EH, Meisamy S, Garwood M. Measurement and correction of respiration-induced B0 variations in breast 1H MRS at 4 Tesla. Magn Reson Med 2004; 52:1239-1245

Meisamy S, Bolan PJ, Baker EH, Bliss RL, Gulbahce E, Everson LI, Nelson MT, Emory TH, Tuttle TM, Yee D, Garwood M. Neoadjuvant chemotherapy of locally advanced breast cancer: predicting response with in vivo 1H MR spectroscopy--a pilot study at 4 T. Radiology 2004; 233:424-431

Bolan PJ, Nelson MT, Yee D, Garwood M. Imaging in Breast Cancer: Magnetic Resonance Spectroscopy. Breast Cancer Research 7:149-152 2005

Meisamy S, Bolan PJ, Baker EH, Pollema MG, Le CT, Kelcz F, Lechner MC, Luikens BA, Carlson RA, Brandt KR, Amrami KK, Nelson MT, Everson LI, Emory TH, Tuttle TM, Yee D, Garwood M. Adding in Vivo Quantitative 1H MR Spectroscopy to Improve Diagnostic Accuracy of Breast MR Imaging: Preliminary Results of Observer Performance Study at 4.0 T. Radiology 2005; 236(2):465-475

Bolan PJ, Yacoub E, Garwood M, Ugurbil K, Harel N. In vivo micro-MRI of intracortical neurovasculature. NeuroImage 2006, 32(1):62-9

Haddadin I, McIntosh A, Meisamy S, Corum C, Styczynski-Snyder A, Powell N, Nelson M, Yee D, Garwood M, Bolan PJ. Metabolite Quantification and High-Field MRS in Breast Cancer. NMR Biomed. 2009 Jan;22(1):65-76

Corum CA, McIntosh AD, Bolan PJ, Nelson M, Snyder AL, Powell NJ, Boyum J, Emory TH, Yee D, Tuttle TM, Everson LI, Garwood M. Feasibility of single-voxel MRS measurement of apparent diffusion coefficient of water in breast tumors. Magn Reson Med. 2009 Feb 23;61(5):1232-1237