Research Program: Transplant Biology & Therapy
Assistant Professor, Hematology, Oncology and Transplantation (HOT) Division

bach0173@umn.edu
Office — 612-625-5469
Preferred method of contact: e-mail

Dr. Bachanova's clinical profile
(University of Minnesota Physicians Web site)

Dr. Bachanova received her medical degree in 1992 from Komenius University, Bratislava, Slovakia. She completed her oncology residency in Bratislava and her internal medicine residency at Henry Ford Hospital in Detroit in 1998. She spent 5 years practicing internal medicine before coming to University of Minnesota to complete a fellowship in medical oncology and hematology. She became a clinical investigator and assistant professor in 2007. Dr. Bachanova is currently a faculty member in the Hematology, Oncology and Transplantation (HOT) Division and chair of the Lymphoma Site Team.

Research Interests

Dr. Bachanova's research interests have focused on malignant hematology and stem cell transplantation. She is interested in tumor immunology of lymphoid malignancies and novel treatment strategies to treat lymphoma and leukemia. Laboratory-based research conducted during her hematology fellowship in the laboratory of Dr. Jeffrey S. Miller showed that Notch pathway is important for the development of Natural Killer cells. Dr. Bachanova's clinical research has focused on expanding the application of adoptive transfer of allogeneic NK cells to treat non-Hodgkin lymphoma and chronic lymphocytic leukemia (CLL). In addition to clinical trials development, she works with Dr. Miller on methods to enhance the graft-versus-tumor effect against tumors.

Selected Publications

Bachanova V, McCullar V, Lenvik T, Wangen R, Peterson KA, Ankarlo DEM, Panoskaltsis-Mortari A, Wagner JE, Miller JS. Activated Notch supports development of cytokines producing NK cells which are hyporesponsive and fail to acquire NK cells effector function. Biol.Blood and Marrow Transplantation. 2009. 15:183-194

Bachanova V, Defor T, Verneris M, Brunstein C, Weisdorf D. Prolonged survival in adults with acute lymphoblastic leukemia (ALL) following reduced intensity conditioning with cord blood or sibling donor transplantation. Blood. 2009. Jan28, 2009 Ahead of print.

Bachanova V, Connors JM. How is hodgkin lymphoma in pregnancy best treated? Hematology Am Soc Hematol Educ Program. 2008;2008:33-4

Bachanova V, Weisdorf D. Unrelated donor allogeneic transplantation for adult acute lymphoblastic leukemia: a review. Bone Marrow Transplant. 2007; Mar;41(5):455-64

Bachanova V, Kunova A, Sycova Z, Salek T. Itraconazole versus fluconazole in the treatment of oropharyngeal candidiasis in cancer patients. Acta Chemotherapeutika. 1994;3:11-17

Studena V, Sycova Z, Helpianska L, Sorkovska D, et al. Fluconazole versus itraconazole in therapy of oropharyngeal candidiasis in cancer patients: a prospective comparative randomized trial. Journal of Chemotherapy 1995; 7(sup.4):145-J46.5