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Clinical Trials

Protocol Number Title
1996CG033
CALGB 8461 Cytogenetic studies in acute leukemia
1996LS132
Allogeneic bone marrow transplantation for chronic myelogenous leukemia in chronic or accelerated phase MT1982-12
1996LS275
MT1992-20: Aplastic anemia or osteopetrosis: Preparation for marrow transplantation. Standard of Care
1999CG016
D9902 A group wide protocol for collecting and banking pediatric cancer research specimens: An IRSG protocol CCG D9902
1999LS032
MT1999-08 Cytosine arabinoside and mitoxantrone for patients with juvenile myelomonocytic leukemia receiving repeat stem cell transplantation
1999LS060
MT1999-14 Unrelated or partially matched allogeneic donor stem cells for lymphoma, myeloma, and chronic lymphocytic leukemia
1999LS073
MT1999-20 Hematopoietic cell transplantation in children with juvenile myelomonocytic leukemia
2000LS040
MT2000-12 Busulfan, Cyclophosphamide, and Melphalan Followed by Allogeneic Hematopoietic Cell Transplantation in Patients with Hematological Malignancies
2001CG051
ANBL0032 Phase III Randomized Study of Chimeric Antibody 14.18 (Ch14.18) in High-Risk Neuroblastoma Following Myeloablative Therapy and Autologous Stem Cell Rescue
2001LS049
MT2001-02: Allogeneic Transplant for Hematological Malignancy
2001LS058
MT2001-10 Allogeneic Bone Marrow Transplant Using Less Intensive Therapy
2002LS014
Hematopoietic Stem Cell Transplantation in High Risk Patients with Fanconi Anemia MT2002-02
2002LS032
MT1999-06: Vaccination with Tetanus Toxoid and Keyhold Limpet Hemocyanin (KLH) to Assess Antigen-Specific Immune Responses
2002LS097
Twin Cities Brachytherapy Study for Ductal Carcinoma in Situ: A Phase II Trial
2003CG061
AGCT0132 A Phase III Study of Reduced Therapy in the Treatment of Children with Low and Intermediate Risk Extracranial Germ Cell Tumors
2003NT024
GOG Protocol 0210: A Molecular Staging Study of Endometrial Carcinoma
2003NT028
COG AALL03B1: Classification of Acute Lymphoblastic Leukemia
2003NT030
Sentinel Lymph Node Biopsy before Preoperative Chemotherapy: Factors Associated with Non-Sentinel Lymph Node Metastases
2003NT036
ALTE03N1 Key Adverse Events After Childhood Cancer (COG study)
2003NT047
CALGB 140202: The CALGB Lung Cancer Tissue Bank
2003NT049
ABTR01B1 A Children's Oncology Group Protocol for Collecting and Banking Pediatric Research Specimens Including Rare Pediatric Tumors
2003NT050
ACNS02B3 A Children's Oncology Group Protocol for Collecting and Banking Pediatric Brain Tumor Research Specimens
2003NT051
COG 9346 Hepatoblastoma Biology Study and Tissue Bank
2003NT056
Methods for Tobacco Exposure Reduction in Human - Study 2: Comparisons of Nicotine-Free Cigarettes, Extra Low Nicotine Cigarette vs. Medicinal Nicotine; Part of Hatsukami's Tobacco Exposure Reduction
2003NT064
Metabolic Syndrome in Childhood Cancer Survivors
2004CG009
COG AALL0232 "HighRisk B-precursor Acute Lymphoblastic Leukemia"
2004CG029
COG ACNS0331: A Study Evaluating Limited Target Volumne Boost Irradiation and Reduced Dose Craniospinal Radiotherapy (18.00 Gy) and Chemotherapy in Children with Newly Diagnosed Standard Risk Medulloblastoma: A Phase III Double Randomized Trial
2004CG064
COG ARST0331: Vincristine, Dactinomycin, and Lower Doses of Cyclophosphamide With or Without Radiation Therapy for Patients with Newly Diagnosed Low-Risk Embryonal/Botryoid/Spindle Cell Rhabdomyosarcoma
2004LS001
MT2003-13 Autologous Transplantation for Multiple Myeloma
2004LS006
MT2003-15 Use of Cyclophosphamide/Fludarabine to Promote in vivo Expansion of Donor Lymphocyte Infusion s(DLI) to Enhance Efficacy after Allogeneic Transplant
2004LS034
MT2004-03: A Dose Escalation Study of CD4+ CD25+ Cells in Adult Patients Undergoing HLA-Identical Sibling Donor Peripheral Blood Progenitor Cell (PBPC) Transplantation" MT2004-03: A Clinical Trial of Adult CD4+ CD25+ Regulatory T Cells in BMT Recipients
2004LS042
MT2003-23: Reduced Intensity Haploidentical Hematopoietic Stem Cell Transplantation (HSCT) Supplemented with Donor Natural Killer (NK) Cell Infusions in Patients with High Risk Myeloid Malignancies who are Unsuitable for Fully Myeloablative Transplantation with a Phase II, Open Label Study of Bortezomib in the Preparative Regimen
2004LS060
A Phase II Pilot Study of Multi-Agent Neo Adjuvant Chemoradiation in Patients with Locally Advanced Pancreatic Adenocarcinoma
2004UC035
MT2004-04: A Multicenter, Prospective Trial to Evaluate the Role of NK Cell Kir Epitope Mismatch on Mortality and Disease Relapse in T-Cell Depleted Hematopoietic Stem Cell Transplantation for HLA-C Mismatch, Unrelated Donors for Myeloid Malignancies
2005CG018
COG ADVL04P2: A Feasibility Pilot and Phase II Study of Chemoimmunotherapy with Epratuzumab (IND#12034) for Children with Relapsed CD22-positive Acute Lymphoblastic Leukemia (ALL)
2005CG028
COG AALL0331: Standard Risk B-Precursor Acute Lymphoblastic Leukemia
2005CG061
MT2005-22: Fludarabine-Based Conditioning for Allogeneic Marrow Transplantation from HLA-Compatible Unrelated Donors in Severe Aplastic Anemia (CTN 0301)
2005LS006
Breast MRI Assessment of Tumor Viability After Radiofrequency Ablation (RFA)
2005LS023
MT2004-30: Dose Escalation of Total Marrow Irradiation Added To An Alkylator-Intense Conditioning Regimen For Patients with High Risk or Relapsed Solid Tumors
2005LS036
MT2005-02: Transplantation of Unrelated Donor Umbilical Cord Blood in Patients with Hematological Malignancies Using a Non-Myeloablative Preparative Regimen
2005LS043
MT2005-10: Transplantation of Unrelated Umbilical Cord Blood for Patients with Hematological Diseases with Cyclophosphamide/Fludarabine/Total Body Irradiation Myeloblative Preparative Regimen
2005LS048
MT2004-24: Autologous Peripheral Blood Stem Cell Transplant for Patients with Lymphoma
2005LS068
Phase I Hyperthermic Intraperitoneal Oxaliplatin for Peritoneal Malignancies
2005LS075
MT2005-25: Hematopoietic Stem Cell Transplantation in the Treatment of Infant Leukemia
2005LS080
An Evaluation of PET CT Imaging as a Predictor of Response to Preoperative Chemotherapy for Soft Tissue Sarcoma
2005LS083
Phase II Clinical Study of Weekly Topotecan in Combination with Bevacizumab in Patients with Stage IIIB/IV Non-Small Cell Lung Cancer Who Have Failed Prior Systemic Chemotherapy
2005NT018
A Randomized Phase II Study of Zoledronic Acid (Zometa) in the Prevention of Osteoporosis In Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation (Study # CZOL446EUS29, MT2005-06)
2005NT019
A Non-Interventional Prospective Study of the Correlation of the Precision Therapeutics, Inc. Chemoresponse Assay with Progression-free Survival in Patients with Recurrent Epithelial Ovarian, Peritoneal or Fallopian Tube Cancer
2005NT023
Capillary Electrophoresis of HCCC (Hepatocellular Carcinoma) Lesions, Untreated and Treated with Chemoembolization Containing Doxorubicin
2005NT026
AALL03N1 Understanding the Ethnic and Racial Differences in Survival Among Children with Acute Lymphoblastic Leukemia
2006CG003
COG AOST0331: A Randomized Trial of the European and American Osteosarcoma Study Group to Optimize Treatment Strategies for Resectable Osteosarcoma Based on Histological Response to Pre-Operative Chemotherapy
2006CG023
COG ARET0332: A Study of Unilaterial Retinoblastoma with and without Histopathologic High-Risk Features and the Role of Adjuvant Chemotherapy
2006CG033
COG ADVL0413: A Phase I Study of the RAF Kinase and Receptor Tyrosine Kinase Inhibitor Sorafenib (BAY 43-9006, NSC# 724772, IND# 69896) in Children with Refractory Solid Tumors or Refractory Leukemias
2006CG044
MT2006-18 (CTN 0402): A Phase III Randomized, Multicenter Trial Comparing Sirolimus/Tacrolimus with Tacrolimus/Methotrexate as Graft-Versus-Host Disease (GVHD) Prophylaxis after HLA-Matched, Related Peripheral Blood Stem Cell Transplantation
2006CG045
CTSU/ECOG PAACT-1: Program for the assessment of clinical cancer tests (PACCT-1) trial assigning individualized options for treatment: the TAILORx trial
2006CG059
MT2006-26 COG AAML0531: A Phase III Randomized Trial of Gemtuzumab Ozogamicin Combined with Conventional Chemotherapy for De Novo Acute Myeloid Leukemia (AML) in Children, Adolescents, and Young Adults
2006CG060
ECOG 2805: ASSURE: Adjuvant Sorafenib or Sunitinib for Unfavorable Renal Carcinoma
2006IS006
A prospective, randomized, double-blind, stratified, multi-center, 2-arm trial of the continued efficacy and safety of Zometa (every 4 weeks vs. every 12 weeks) in patients with documented bone metastases from breast cancer (Study No. CZOL446E2352)
2006IS047
A Phase 1 Pharmacodynamic Study of CP-751,871 as Neoadjuvant Treatment for Early Breast Cancer
2006LS016
Phase II Study of Naltrexone for the Treatment of Hormone-Refractory, Metastatic Breast Cancer
2006LS032
MT2005-21: Autologous Peripheral Blood Stem Cell Transplant for Germ Cell Tumors
2006LS046
A Randomized Phase II Study of IL-2 With or Without an Allogeneic Large Multivalent Immunogen (LMI) Vaccine for the Treatment of Stage IV Melanoma
2006LS057
MT2006-09: Phase I Open Label, Single Arm Escalation Trial to Evaluate the Biodistribution and Safety of BU-12 in Patients with Advanced Leukemia
2006LS058
MT2006-20 CTN 0501 - Multi-center, Open Label, Randomized Trial Comparing Single Versus Double Umbilical Cord Blood (UCB) Transplantation in Pediatric Patients with Leukemia and Myelodysplasia
2006NT001
Biomarker with Biological Function in Ovarian Carcinoma/Diagnostic Markers for Ovarian Cancer: Detection of Novel Cell Adhesion Proteins in Patients' Specimens
2006NT007
Diagnostic Prostate Magnetic Resonance Imaging at 3 Tesla with an Endorectal Coil
2006NT012
MT2006-27: Bone Mineral Resorption In Children After Hematopoetic Stem Cell Transplantation
2006NT014
Bupropion + Placebo or Bupropion + Naltrexone for Smoking Cessation
2006NT018
Menstrual Phase and Depression Symptoms in Acute Smoking Abstinence
2006NT021
Secreted Biomarkers in Prostate Cancer Detection and Identification of Cancer Altered Proteins in Human Prostate Secretions
2006NT036
MT2007-16R Pilot Study of Vascular Function During Hematopoietic Cell Transplantation
2006UC008
MT2006-04: Head Start III: Dose Intensive Chemotherapy for Children Less than Ten Years of Age Newly Diagnosed with Malignant Brain Tumors: A Pilot Study of Two Alternative Intensive Induction Chemotherapy Regimens, Followed by Consolidation with Myeloablative Chemotherapy (Thiotepa and Carboplatin, with or without Etoposide) and Autologous Stem Cell Rescue
2006UC048
Phase I and II Study of Stereotactic Body Radiation Therapy (SBRT) for Low and Intermediate Risk Prostate Cancer
2007CG010
COG ADVL0612: A Phase I Study of Sunitinib, an Oral Multi-Targeted Tyrosine Kinase Inhibitor, in Children with Refractory Solid Tumors
2007CG012
GOG Protocol 0212: A Randomized Phase III Trial of Maintenance Chemotherapy Comparing 12 Monthly Cycles of Single Agent Paclitaxel or CT-2103 (IND#70177) Versus No Treatment Until Documented Relapse in Women with Advanced Ovarian, Primary Peritoneal or Fallopian Tube Cancer Who Achieve a Complete Clinical Response to Primary Platinum/Taxane Chemotherapy
2007CG023
MT2006-25: CTN 0403 - A Randomized Double-Blind, Placebo-Controlled Trial of Soluble Tumor Necrosis Factor Receptor: Enbrel (Etanercept) for the Treatment of Acute Non-Infectious Pulmonary Dysfunction (Idiopathic Pneumonia Syndrome) Following Allogeneic Cell Transplantation
2007CG034
COG AALL0434: Intensified Methotrexate, Nelarabine and Augmented BFM Therapy for Children and Young Adults with Newly Diagnosed T-cell Acute Lymphoblastic Leukemia (ALL)
2007CG038
COG ARST0531: Randomized Study of Vincristine, Dactinomycin, and Cyclophosphamide (VAC), versus VAC Alternating with Vincristine and Irinotecan for Patients with Intermediate Risk Rhabdoymyosarcoma
2007CG045
Erwinase Master Treatment Protocol (erwinia asparaginase)
2007CG049
COG AHOD03P1: Treatment of Children with Newly Diagnosed Low Stage Lymphocyte Predominant Hodgkin Disease (LPHD)
2007CG050
CALGB 50401: A randomized phase II trial of rituximab vs. lenalidomide (Revlimid, CC-5013) vs. rituximab + lenalidomide in recurrent follicular non-Hodgkin lymphoma (NHL) that is not rituximab-refractory
2007CG051
CALGB 10602: A randomized phase II trial of azacytidine with or without the histone deacetylase inhibitor entinostat for the treatment of myelodysplastic syndrome, chronic myelomonocytic leukemia (dysplastic type), and acute myeloid leukemia with multilineage dysplasia.
2007CG058
COG AALL0433: Intensive Treatment for Intermediate-Risk Relapse of Childhood B-Precursor Acute Lymphoblastic Leukemia (ALL): A Randomized Trial of Vincristine Strategies
2007CG068
COG AAML0431: The Treatment of Down Syndrome Children with Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) Under the Age of 4 Years
2007CG075
COG AREN0532: Treatment for Very Low, Low, and Secondary Risk Favorable Histology Wilms Tumor.
2007CG076
ASCT0521: Phase II Open Label Study Tumor Necrosis Factor Receptor: Enbrel (Etanercept) for the Treatment of Acute Non-Infectious Pulmonary Dysfunction (Idiopathic Pneumonia Syndrome) Following Allogeneic Stem Cell Transplant.
2007CG077
SARC006: Phase II Trial of Chemotherapy in Sporadic and Neurofibromatosis Type 1 Associated with High Grade Unresectable Malignant Peripheral Nerve Sheath Tumors
2007CG081
ECOG 1505: A Phase III Randomized Trial of Adjuvant Chemotherapy With or Without Bevacizumab for Patients with Completely resected Stage 1B (>/= 4 cm) - Non- Small Cell Lung Cancer.
2007CG083
CALGB 140503: Phase III Randomized Trial of Lobectomy Versus Sublobar Resection for Small (<2 cm) Peripheral Non-Small Cell Lung Cancer
2007CG096
ARST0332 - Risk-Based Treatment for Non-Rhabdomyosarcoma Soft Tissue Sarcomas (NRSTS) in Patients Under 30 Years of Age
2007CG113
COG ACNS0332: Efficacy of Carboplatin Administered Concomitantly with Radiation and Isotretinoin as a Pro-Apoptotic Agent in Other Than Average Risk Medulloblastoma/PNET patients.
2007IS025
A two-arm randomized open label phase 2 study of CP-751, 871 in combination with exemestane versus exemestane alone as a first line treatment for postmenopausal patients with hormone receptor positive advanced breast cancer (Pfizer A4021004)
2007IS026
A Phase III, Multicenter, Randomized, Blinded, Placebo-Controlled Trial of Carboplatin and Gemcitabine Plus Bevacizumab in Patients with Platinum-Sensitive Recurrent Ovary, Primary Peritoneal, or Fallopian Tube Carcinoma (AVF4095g)
2007IS041
Phase II Study of the Trifunctional Bispecific Anti-HER-2/Neu x Anti-CD3 Antibody Ertumaxomab in Patients with HER-2/Neu Overexpressing (3+ by Dako Hercep Test? or FISH+) Metastatic Breast Cancer Progressing after Trastuzumab Treatment
2007IS056
A double-blind, randomized, placebo-controlled phase III study to assess the efficacy of recMAGE-A3 + AS15 Antigen Specific Cancer Immunotherapeutic as Adjuvant Therapy in Patients with Resectable MAGE-A3-positive Non-Small Cell Lung Cancer (GSK 109493)
2007IS088
A Multi-Center, Open-Label, Randomized, Phase II/III Study to Evaluate the Safety and Efficacy of Combretastatin A-4 Phosphate in Combination with Paclitaxel and Carboplatin in Comparison with Paclitaxel and Carboplatin Against Anaplastic Thyroid Carcinoma (OXiGENE OXC4T4-302)
2007IS095
Protherics PR001-CLN-pro016: An Open Label Treatment Protocol for the Use of Voraxase as Adjunctive Treatment for Patients Experiencing or Are At Risk of Methotrexate Toxicity.
2007IS117
Amgen 20050252: A Phase I Study to Evaluate the Safety and Pharmacokinetics of Panitumumab in Children with Solid Tumors
2007IS134
Registration Phase III Study of Lucanix (Belagenpumatucel-L) in Advanced Non-small Cell Lung Cancer: An International Multicenter, Randomized, Double-blinded, Placebo-controlled Study of Lucanix Maintenance Therapy for Stages III/IV NSCLC Subjects Who Have Responded to or Have Stable Disease Following One Regimen of Front-line, Platinum-based Combination Chemotherapy (NovaRx NR001-03)
2007LS019
Phase I Clinical Trial of Trametes Versicolor in Women with Breast Cancer
2007LS022
MT2006-01: Phase I Study of Infusion of Umbilical Cord Blood (UCB) Derived CD25+ CD4+ T-Regulatory (Treg) Cells After Non-Myeloablative Cord Blood Transplantation
2007LS064
MT2007-12: Allogeneic Natural Killer Cells with Rituximab in Patients with CD20 Positive Relapsed Non-Hodgkin Lymphoma or Chronic Lymphocytic Leukemia ALSO -- Strategies to Increase Sensitivity of CLL Tumor Cells to Natural Killer Cell-Immune-Mediated Cytolysis
2007LS065
MT2007-11R: Open-Label Single-Arm Pilot Study of Deferasirox (Exjade) in Adult Allogenic Hematopoietic Stem Cell Transplant Recipients with Transfusional Iron Overload
2007LS072
MT2007-07: Conditioning for Graft Failure after Hematopoietic Stem Cell Transplantation
2007LS094
A Phase II Study of an Allogeneic Large Multivalent Immunogen (LMI) Vaccine for the Treatment of Stable, Metastatic Breast Cancer
2007NT029
Genetic Epidemiology of Osteosarcoma
2007NT032
Human Laboratory Study of Varenicline in Smokers
2007NT042
The clearance of tobacco carcinogen biomarkers after smoking cessation
2007NT053
Promoting Home Smoking Restrictions: Biomarker Feedback to Cohabitating Smoking and Non-Smoking Adults.
2007NT059
ABTR06C1: Pharmakokinetics of Daunomycin in Children
2007NT070
The Pharmacokinetics of a 41 Ca Marker for Bone Turnover in Breast Cancer Patients Treated with an Aromatase Inhibitor and Bisphosphonate.
2007NT078
Empowering Cancer Survivors through Information Technology
2007NT079
Neurocognitive and White Matter Changes in Adult Allogeneic Non-myeloblative Hematopoietic Cell Transplant Survivors: A Pilot Study
2007NT080
Magnetic Resonance Imaging of the Prostate at 7 Tesla
2007NT085
COG ACCL05C1: A Group-Wide Prospective Study of Ototoxicity Assessment in Children Receiving Cisplatin Chemotherapy.
2007NT091
COG AREN03B2: Renal Tumors Classification, Biology and Banking Study.
2007NT092
AHOD04B1 Hodgkin's Disease Banking Study
2007NT093
Determining and comparing the pharmacokinetics of deuterated phenanthrene in smokers after oral dosing and incorporation into cigarettes
2007NT102
COG AALL05B1: A Children's Oncology Group Protocol for Collecting and Banking Relapsed Acute Lymphoblastic Leukemia Research Samples.
2007NT121
A Phase I Open-Label Study of the Safety and Pharmacokinetics of Repeated-Dose Micafungin (FK463) in Children (2-5yrs and 6-11 yrs) and Adolescents (12-16 yrs.) with Esophageal Candidiasis or other Invasive Candidiasis (Astellas 9463-CL-2101)
2007NT123
2007-18R: Chronic GVHD Cohort Protocol
2007NT126
CALGB 150007: Contrast Enhanced Breast MRI and Correlative Science Studies to Characterize Tumor Response in Patients Undergoing Neoadjuvant Treatment for Locally Advanced Breast Cancer- RUNS IN TANDEM WITH CALGB 150012, PLEASE SEE 2007NT140 FOR COMPLETE INFORMATION FOR BOTH PROTOCOLS.
2007NT127
Randomized Trial of PEITC as a Modifier of NNK Metabolism in Smokers
2007NT129
Oral Tobacco as Harm Reduction Method for Smokers: Study 1: Preference, Health Effects and Efficacy of Four Oral Tobacco Products for Smoking Cessation
2007NT140
CALGB 150012: Contrast-Enhanced Breast MRI and MRS for Evaluation of Patients Undergoing Neoadjuvant Treatment for Locally Advanced Breast Cancer. (Must be Enrolled in CALGB 150007)
2007NT148
Fetal Cells Present in the Maternal Circulation
2007NT151
Quality of Life in Survivors of Non-Hodgkins Lymphoma
2007NT158
Community Based Dialogue for Action Against Colorectal Cancer in Minnesota American Indians
2007NT160
Tobacco Treatment Among Racial./Ethnic Minority Smokers
2007NT162
Improving The School Food Environment - Part 2 and Part 3
2007NT167
Development and Validation of Methods to Increase Parent Participation in School Welllness Policy Initiatives in Utah - Part 3
2007UC002
MT2006-07 Reduced Intensity Hematopoietic Cell Transplantation for Patients with Resistant Langerhans Cell Histiocytosis
2008CG030
ANBL0531 Response-and Biology-based Therapy for Intermediate-risk Neuroblastoma
2008CG045
CALGB 50501: A Phase II Trial of Bortezomib (NSC #681239) + Lenalidomide (RevlimidTM, CC-5013) (NSC #703813) for Relapsed/Refractory Mantle Cell Lymphoma
2008CG046
CALGB 10403 An Intergroup Phase II Clinical Trial for Adolescents and Young Adults with Untreated Acute Lymphoblastic Leukemia
2008CG048
MT2008-07R: 07-REV: Evaluation of Lenalidomide as Maintenance Therapy Post Allogeneic Hematopoietic Cell Transplantation for High Risk Multiple Myeloma
2008CG050
COG AALL07P2 Pharmacology and Toxicity of Erwinia Asparaginase (Erwinase; Cristantaspase; IND 290) Following Allergy to PEG-Asparaginase in Treatment of Children with Acute Lymphoblastic Leukemia (ALL)
2008CG069
COG ADVL0714 "A Phase I Study of VEGF Trap (NSC# 724770, IND #100137) in Children with Refractory Solid Tumors"
2008CG076
CALGB 30504: Combination Chemotherapy With or Without Maintainence Sunitinib Malate (IND 74019; NSC 736511) for Untreated Extensive Stage Small Cell Lung Cancer: A phase IB/Randomized Phase II study
2008CG099
MT2008-30: A Multi-Center, Phase II Trial of Non-Myeloablative Conditioning (NST) and Transplantation of Umbilical Cord Blood (UCB) from Unrelated Donors in Patients with Hematologic Malignancies (2008-30)
2008CG100
COG AALL0631: A Phase III Study of Risk Directed Therapy for Infants with Acute Lymphoblastic Leukemia (ALL): Randomization of Highest Risk Infants to Intensive Chemotherapy +/- FLT3 Inhibition (CEP-701, Lestaurtinib; IND#76431; NSC#617807)
2008CG102
CALGB 30704 A Randomized Phase II Study to Assess the Efficacy of Pemetrexed or Sunitinib (NSC#736511, IND#74019) or Pemetrexed Plus Sunitinib in the Second-line Treatment of Advanced Non-small Cell Lung Cancer
2008CG125
COG AAML07P1 A Phase II Pilot Study of Bortezomib (PS-341, Velcade) Combined with Reinduction Chemotherapy in Children and Young Adults with Recurrent, Refractory or Secondary Acute Myeloid Leukemia
2008CG146
GOG 0251: Phase II Trial of NCI-Supplied Agent: Bevacizumab for Recurrent Sex Cord-Stromal Tumors of the Ovary
2008CG153
MT2008-42: Phase II Trial of Non-Myeloablative Allogeneic Hematopoietic Cell Transplantation for Patients with Relapsed Follicular Non-Hodgkin's Lymphoma Beyond First Complete Response
2008CG157
COG AREN0533 Treatment of Newly Diagnosed Higher Risk Favorable Histology Wilms Tumors
2008CG164
COG ADVL0812 A Phase I Study of MLN8237, an Oral Selective Small Molecule Inhibitor of Aurora A Kinase, in Children with Relapsed/Refractory Solid Tumors and Leukemia
2008IS026
A Randomized, Open-Label, Multinational Phase 3 Trial Comparing Amrubicin Versus Topotecan in Patients with Extensive or Limited and Sensitive or Refractory Small Cell Lung Cancer After Failure of First-Line Chemotherapy (Pharmion: AMR-PH-GL-2007-CL-001)
2008IS028
A Study to Determine the Activity of SCH 717454 in Subjects with Osteosarcoma or Ewing's Sarcoma that has Relapsed After Standard Systemic Therapy
2008IS034
A Prospective, Randomized Trial Comparing the Efficacy of Anidulafungin and Voriconazole in Combination to that of Voriconazole Alone When Used for Primary Therapy of Proven or Probable Invasive Aspergillosis
2008IS061
A Phase III Randomized, Double-Blind, Placebo-Controlled Study of Sorafenib and Adjuvant Treatment for Hepatocellular Carcinoma After Surgical Resection or Local Ablation
2008IS063
A Phase 1b Study of LY573636-Sodium in Combination with Sunitinib Malate in Patients with Metastatic Renal Cancer
2008IS066
Axitinib (AG-013736) as Second Line Therapy for Metastatic Renal Cell Cancer: Axis Trial
2008IS067
A Pivotal Trial to Determine the Efficacy and Safety of AP23573 When Administered as Maintenence Therapy to Patients with Metastatic Soft Tissue or Bone Sarcomas
2008IS072
A Multicenter, Randomized, Double-Blind, Phase 3 Study of Sunitinib Plus Prednisone versus Prednisone in Patients with Progressive Metastatic Hormone Refractory Prostate Cancer After Failure of a Docetaxel-Based Chemotherapy Regimen
2008IS084
A Phase II Study of HyperAcute Pancreatic Cancer Vaccine in Combination with Chemotherapy and Chemoradiotherapy in Subjects with Surgically Resected Pancreatic Cancer
2008IS086
MT2008-26: Defibrotide for Hematopoietic Stem Cell Transplant (SCT) Patient With Severe Hepatic Veno-occlusive Disease (VOD): A Treatment IND Study (Under CFR 312.34)
2008IS090
H3E-MC-JMIG: Phase III Study of Pemetrexed, Cisplatin, and Radiotherapy Followed by Consolidation Pemetrexed versus Etoposide, Cisplatin and Radiotherapy Followed by Consolidation Cytotoxic Chemotherapy of Choice in Patients with Unresectable, Locally Advanced, Stage III Non-Small Cell Lung Cancer Other than Predominantly Squamous Cell Histology
2008IS091
A Randomized, Multicenter, Phase II Study of the Efficacy and Safety of Trastuzumab-MCC-DMI vs Trastuzumab (Herceptin?) and Docetaxel (Taxotere?) in Patients with Metastatic Her2-Positive Breast Cancer Who Have Not Received Prior Chemotherapy for Metastatic Disease (TDM4450g)
2008IS096
VEG108844 A Study of Pazopanib Versus Sunitinib in the Treatment of Subjects with Locally Advanced and/or Metastatic Renal Cell Carcinoma
2008IS117
A double-blind, randomized, placebo-controlled Phase III study to assess the efficacy of recMAGE-A3 + AS15 ASCI as adjuvant therapy in patients with MAGE-A3 positive resected stage III melanoma (GSK 2132231)
2008IS118
A Randomized Double Blind Phase III Trial of Pazopanib Versus Placebo in Patients With Soft Tissue Sarcoma Whose Disease Has Progressed During or Following Prior Therapy
2008IS123
An Open-label, Multi-center, Phase 2 Study of Denosumab in Subjects with Giant Cell Tumor of Bone
2008IS151
A Phase IIIb Open-Label, Multi-Centre Immunization Study to Evaluate the Safety of GlaxoSmithKline (GSK) Biologicals' HPV-16/18 L1 VLP AS04 Vaccine Administered Intramuscularly According to a 0,1,6-Month Schedule in Female American and Canadian Subjects Who Received the Active Control Hepatitis A Vaccine in the 580299/008 Study
2008LS035
Phase I-II Trial of Genistein in Subjects Receiving Palliative External Beam Radiation Therapy for Osseous Metastases: A Study of Palliation of Symptoms and Quality of Life
2008LS043
Phase II Trial of Bortezomib and Rituximab for Patients with Post Transplant Lymphoproliferative Disorders (PTLD) MT2008-05R
2008LS044
MT2008-06R: Phase II Trial of Velcade Plus Vorinostat in the Treatment of High Risk MDS and Relapsed/Refractory AML
2008LS047
WCC #50 - Phase I Trial of Lenalidomide in Combination with Liposomal Doxorubicin for the Treatment of Recurrent Epithelial Ovarian, Fallopian Tube and Primary Peritoneal Cancer
2008LS110
MT2008-36: Haploidentical Donor NK Cell Adoptive Therapy and Double T Cell Depleted Umbilical Cord Blood Transplantation With Post-Transplant IL-2 Immune Therapy For Refractory Acute Myeloid Leukemia
2008LS112
A Therapeutic Trial of Decitabine (Dacogen) and Vorinostat (SAHA) in Combination with Chemotherapy (Vincristine, Prednisone, Doxorubicin and PEG-Asparaginase) for Relapsed/Refractory Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Lymphoma (LL) MT2008-29R
2008LS139
MT2008-38: A Phase I Trial to Determine Safety and Tolerability of Ex Vivo Expanded Human Myeloid Progenitor Cells (CLT-008) Infused 24 Hours Post-Transplant to Support Allogeneic Umbilical Cord Blood Transplantation for Hematologic Malignancies
2008NT001
Biomarker Feedback for Smoking Cessation
2008NT003
Improving NRT Adherence and Outcomes in Homeless Smokers
2008NTCG058
COG AEWS07B1 A Children's Oncology Group Protocol for Collecting and Banking Ewing Sarcoma Specimens
2008NTCG059
AALL06N1 A Study of Neurocognitive Function in Children Treated for ALL
2008NTCG085
COG AOST06B1 A Children's Oncology Group Protocol for Collecting and Banking Osteosarcoma Specimens
2008NTCG101
COG ANBL00B1 "Neuroblastoma Biology Studies"
2008NTCG128
COG ADVL06B1 A Pharmacokinetic-Pharmacodynamic-Pharmacogenetic Study of Actinomycin-D and Vincristine in Children with Cancer
2008NTCG149
GOG 0215: A Phase II Randomized Study of the Effect of Zoledronic Acid Versus Observation on Bone Mineral Density of the Lumbar Spine in Women Who Elect to Undergo Risk-Reducing Surgery That Results in Removal of Both Ovaries
2008NTCG161
COG ACCL0731 Glutamic Acid to Decrease Vincristine Toxicity in Children with Cancer
2008NTLS060
The Effect of Enalapril on Doxorubicin Exposure in Adjuvant Breast Cancer Treatment
2008NTLS087
2008-13R: In Vivo Measurement of DNA and Protein Adducts in Fanconi Anemia and Non-Fanconi Anemia Patients Undergoing Hematopoietic Stem Cell Transplantation
2008NTLS093
Efficacy of an Energy Conservation Course for Persons with Bone Marrow Transplants
2008NTLS103
Iron Overload in Allgeneic Hematopoietic Cell Transplantation
2008NTLS104
Observational Study of Swallowing Function After Treatment of Advanced Laryngeal Cancer
2008NTLS109
Clinical Response to Biomarker Documentation of Child Secondhand Smoke Exposure
2008UC162
MT2008-41 A Pilot Study of Matched Unrelated Donor Hematopoietic Stem Cell Transplant for Patients with High Risk Sickle Cell Disease and Other Non-Malignant Red Cell Disorders Using a Reduced Intensity Preparative Regimen and Haplo-Identical Mesenchymal Stromal Cells to Achieve Stable Mixed Chimerism
2009CG014
COG ADVL0821 A Phase II Study of IMC-A12 (Anti-IGF-I Receptor Monoclonal Antibody, IND# 100947, NSC# 742460) in Children With Relapsed/Refractory Solid Tumors
2009CG019
GOG 240: A Randomized Phase III Trial of Cisplatin Plus Paclitaxel With and Without NCI-Supplied Bevacizumab (NSC #704865, IND #7921)Versus the Non-Platinum Doublet, Topotecan Plus Paclitaxel, With and Without NCI-Supplied Bevacizumab, in Stage IVB, Recurrent or Persistent Carcinoma of the Cervix
2009CG030
GOG 249: A Phase III Trial of Pelvic Radiation Therapy Versus Vaginal Cuff Brachytherapy Followed by Paclitaxel/Carboplatin Chemotherapy in Patients with High Risk, Early Stage Endometrial Carcinoma
2009CG038
COG ADVL0813, A Phase I Study of IMC-A12 (Anti-Insulin-Like Growth Factor-I Receptor Monoclonal Antibody) in Combination with CCI-779 (Temsirolimus) in Pediatric Patients with Recurrent or Refractory Solid Tumors
2009CG061
CALGB 30506 A Randomized Phase III Trial of Adjuvant Therapy in Earlystage Non-Small Cell Lung Cancer Evaluating the Potential Utility of a Genomic Prognostic Model to Identify Patients as Candidates for Adjuvant Chemotherapy
2009CG113
ADVL0912: A Phase 1/2 Study of PF-02341066, an Oral Small Molecule Inhibitor of Anaplastic Lymphoma Kinase (ALK) and C-Met, in Children with Relapsed/Refractory Solid Tumors and Anaplastic Large Cell Lymphoma
2009IS008
A Randomized Phase III Study of Weekly ABI-007 Plus Gemcitabine Versus Gemcitabine Alone in Patients With Metastatic Adenocarcinoma of the Pancreas
2009IS048
An Open-label, Multicenter, Phase III Trial of ABI-007 vs Dacarbazine in Previously Untreated Patients with Metastatic Malignant Melanoma (Abraxis BioScience CA033)
2009NTCG002
Pilot Study of Financial impact of Allogeneic Stem Cell Transplant
2009NTCG017
COG ACCL0431 A Randomized Phase III Study of Sodium Thiosulfate for the Prevention of Cisplatin-Induced Ototoxicity in Children
2009NTCG026
COG ALTE05N1 Umbrella Long-Term Follow-Up Protocol
2009NTCG043
GOG 214: Phase II Double Blind Randomized Trial Evaluating the Biological Effect of Levonorgestrel on the Ovarian Epithelium in Women at High Risk for Ovarian Cancer
2009NTLS024
Diagnostic Magnetic Resonance Imaging and Spectroscopy of the Ovaries at 3 Tesla (T)
2009NTLS077
Green Tea and Reduction of Breast Cancer Risk
2009UC052
T2005-003: A Study of Bortezomib With Chemotherapy for Relapsed/Refractory Acute Lymphoblastic Leukemia
MT2000-09
A Study of Cyclophosphamide, Fludarabine, and Antithymocyte Globulin Followed by Matched Sibling Donor Hematopoietic Cell Transplantation in Patients with Fanconi Anemia
MT2002-07
Allogeneic Hematopoietic Stem Cell Transplant For Patients with High Risk Hemoglobinopathy Using a Non-Myeloablative Preparative Regimen.
MT2002-12
Allogeneic Hematopoietic Stem Cell Transplant for Patients with Immunologic or Histiocytic Disorders Using A Non-Myeloablative Preparative Regimen to Achieve Stable Mixed Chimerism
MT2004-09
Phase II Study of Combined Laronidase (Aldurazyme TM) Enzyme Replacement Therapy (ERT) with Hematopoietic Stem Cell Transplantation (HSCT) for Hurler Syndrome (MPS IH)
MT2006-05
Total Body Irradiation Dose De-Escalation Study in Patients with Fanconi Anemia Undergoing Alternate Donor Hematopoietic Cell Transplantation
MT2006-13
Autologous Peripheral Blood Stem Cell Transplant for Acute Non-Lymphocytic Leukemia (ANLL)
MT2007-05R
Late Effects in Survivors of Stem Cell Transplantation, Pediatric Blood Disorders or Cancer
MT2007-10
Intrathecal Enzyme Replacement Therapy for Patients with Mucopolysaccharidosis Type I (Hurler Syndrome)
MT2008-20
Allogeneic Transplantation For Severe Osteopetrosis

211 trials displayed