About the Genetic Mechanisms of Cancer Program

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The Masonic Cancer Center's Genetic Mechanisms of Cancer (GMOC) research program consists of 34 faculty members at all ranks from 10 different departments within the Medical School on the Minneapolis and Duluth campuses, the School of Dentistry, the College of Science and Engineering, the College of Pharmacy, and the School of Veterinary Medicine.

The scientific goals of the program are to define and understand the genetic changes that occur during cancer development, including the specific changes that drive tumor initiation and progression and those that influence cancer susceptibility.

To achieve these goals, GMOC is focused on three research themes:
  • Cancer gene discovery and analysis: genetics of cancer susciptibility and single nucleotide polymorphism (SNP) analysis, genetic screens for cancer-relevant phenotypes in animal models, functional analysis of cancer genes, and genome-wide analysis of gene expression
  • Genome stability: chromosome segregation; DNA replication, repair and recombination; DNA
  • Cancer gene therapy and genome modification: building animal and human cell-based cancer models, gene therapy

Genetic Mechanisms of Cancer program meetings

Held the second Friday of each month, 12-1 p.m., in 450 MCRB.