(April 18, 2007) Cancer Center researchers and U of M colleagues were among the presenters at the American Association of Cancer Research annual meeting in Los Angeles, April 14-18, 2007. Below is a list of their presentations.

If you or someone from your laboratory gave an oral or poster presentation at AACR that is not listed here, please e-mail Sandi Sherman, sherm019@umn.edu, with your name, title and/or lab affiliation, and the title of your presentation.

Oral Presentations

Science of Supportive Care: Impact on the Quality of life for Cancer Patients

Patrick Mantyh, Ph.D., Professor, Departments of Diagnostic and Biological Sciences, Psychiatry, Neuroscience, "New approaches to pain therapy"

Drug Discover and Design 2: Targeted Design and Delivery

Chengguo Xing, Ph.D., Assistant Professor, Department of Medicinal Chemistry, chaired this minisymposium.

High Impact Late Breaker Session

Andrew Flood, Ph.D., Assistant Professor, Department of Epidemiology, "Dietary patterns and incident colorectal cancer among middle aged Americans: The NIH-AARP Diet and Health Study"

Poster Sessions

Cox-2 and Selenium

Junxuan Lu, Ph.D., Hormel Institute, "Superior in vivo inhibitory efficacy of methyl-selenium than selenomethionine or selenite against human prostate cancer"

Chemical Biology in Carcinogenesis, Therapy, and Drug Delivery

Mingyao Wang, Hecht lab, "Analysis of formaldehyde-DNA adducts in tissues of rates treated with N-nitrosodimethylamine (NDMA) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)"

Stephen Hecht, Ph.D., Professor, Lab Medicine & Pathology, "Tissue-specific accumulation and persistence of pyridyloxobutyl-DNA adducts in rats treated with tobacco-specific nitrosamines"

Shana Sturla, Ph.D., Assistant Professor, Medicinal Chemistry, "Investigating the mechanism of selective toxicity of antitumor acylfulvenes: Identification of depurinating acylfulvene-DNA adducts"

Pramod Upadhyaya, Ph.D., Hecht lab, "Mass spectrometric identification of deoxyadenosine and DNA adducts formed by 5'-hydroxylation of the tobacco-specific carcinogen N'-nitrosonornicotine"

Liu Xiaodan, Sturla lab, "The action of anticancer acylfulvenes on thioredoxin reductase"

Biomarkers of DNA Damage and Repair 1

Logan Spector, Ph.D., Assistant Professor, Pediatrics, "Detection of cotinine in newborn dried blood spots"

Siyi Zhang, Hecht lab, "Detection and quantitation of acrolein-derived 1,N2-propanodeoxyguanosine adducts in human lung using liquid chromatography-tandem mass spectrometry"

Diet, Body Mass Index, and Cancer

Sabrina Peterson, Ph.D., Food Science and Nutrition, "Coffee intake and risk of colorectal cancer in Singapore Chinese"

Blood-based biomarkers

Simona Ognajaovic, Ph.D., Pediatric Epidemiology, "Association between interleukin-9 (IL-9) levels and acute graft versus host disease (GVHD) in AML patients after bone marrow transplantation"

Prevention Research

Andrew Skildum, Ph.D., Rose-Hellekant lab, "Molecular targets of tamoxifen in a growth factor-active ER+/PR- mouse model of mammary tumorigenesis"

Cytosolic Signaling 1

Yong-Yeon Cho, Dong lab, "RSK2 is a key regulator for cell transformation induced by tumor promoters"

Drug Design and Discovery 1

Chengguo Xing, Ph.D., Assistant Professor, Medicinal Chemistry, "Studies on the stability of HA 14-1 - a small molecule antagonist for anti-apoptotic Bcl-2 protein"

Environmental and Dietary Carcinogenesis

Danuta Malejka-Giganti, Ph.D., Professor, Lab Medicine & Pathology, "Tumorigenicity and genotoxicity of 2,7-dinitrofluorene after systemic administration at a low dose level to female rats"

Natural Products 2

Fekadu Kassie, Ph.D., Hecht lab, "Inhibition of lung tumorigenesis in A/J mice by combinations of N-acetyl-S-(N-2-phenethylthiocarbamoyl)-L-cysteine, myo-inositol, indole-3-carbinol, or diindolylmethane"

Late Breaking Poster Session 2

Bin Yin, Ph.D., Largaespada lab, "Genetic dissection of chemoresistance mechanisms and development of reverse strategy in leukemia using cell culture and mouse transplantation models"