Masonic Cancer Center

A comprehensive cancer center designated by the National Cancer Institute

Masonic Cancer Center Update Newsletter

 

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Update is available on the web at http://www.cancer.umn.edu/news/mcc-update-newsletter/index.htm.

Update is an official newsletter of the Masonic Cancer Center for faculty, members, staff, colleagues, and friends.All submissions for the next issue must be sent to mcccom@umn.edu, by noon on Friday for publication the following Monday.

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February 1, 2016

Tuesday Seminar

Tuesday, February 2, 2016, 9-10 a.m., 450 MCRB (simulcast in 1-125 CCRB)
Cardio-Oncology: A new clinical frontier and a novel platform for investigation
Javid Moslehi, M.D., Assistant Professor of Medicine, Director, Cardio-Oncology Program, Vanderbilt Ingram Cancer Center, Vanderbilt University

Host: Anne Blaes, M.D.

A peek at the next seminar:
Tuesday, February 9, 2016, 1-125 CCRB (simulcast in 450 MCRB, Hormel Institute room 155, and Duluth room 112-SMed)
William Elmquist, PharmD, Ph.D., Professor, Department of Pharmaceutics, Director, Brain Barriers Research Center, University of Minnesota, Research member, Tumor Microenvironment Program

Host: Jim McCarthy, Ph.D.

View the calendar for a complete schedule.

In This Issue

News/Announcements

Program Meetings

Professional Education

Events

Funding Announcements and Opportunities

Employment Opportunities


News

Members in the news

Masonic Cancer Center endorses HPV vaccination for cancer prevention
In response to low national vaccination rates for the human papillomavirus (HPV), the Masonic Cancer Center, University of Minnesota has joined all the other 68 National Cancer Institute (NCI)-designated Comprehensive Cancer Centers in issuing a statement urging for increased HPV vaccination for the prevention of cancer. This flows out of the decision by the MCC and the University of Minnesota’s Division of Gynecology Oncology to launch the Minnesota HPV program (MNhpv). MNhpv is partnering with the Minnesota Department of Health and the American Cancer Society on this important cancer-prevention initiative. A summit meeting of stakeholders from across the state will be held on April 25, sponsored by the Masonic Cancer Center and UMN Gynecologic-Oncology to create a plan to increase HPV vaccination rates in Minnesota.

Member receives  grant
Mohammad Saleem (Bhat) Ph.D., Tumor Microenvironment Program and leader of the Molecular Chemoprevention and Therapeutics research section at The Hormel Institute, University of Minnesota, has received a five-year, $1.7 million grant from the National Cancer Institute to continue work on developing new treatments for metastatic prostate cancer disease. 

Members in the journals

  • Heather Nelson, Ph.D., M.P.H., is the corresponding author on the following paper, recently published in Cancer Research:
  • Karin A. Vineretsky, Margaret R. Karagas, Brock C. Christensen, Jacquelyn K. Kuriger-Laber, Ann E. Perry, Craig A. Storm, and Heather H. Nelson. Skin Cancer Risk Is Modified by KIR/HLA Interactions That Influence the Activation of Natural Killer Immune Cells. Cancer Research 2016: [Epub ahead of print].

Several recent publications from Transplant Biology and Therapy Program members are listed below: 

  • Wagner JE, Brunstein CG, Boitano AE, DeFor TE, McKenna D, Sumstad D, Blazar BR, Tolar J, Le C, Jones J, Cooke CP, Bleul CC. Phase I/II Trial of StemRegenin-1 Expanded Umbilical Cord Blood Hematopoietic Stem Cells Supports Testing as a Stand-Alone Graft. Cell Stem Cell 2016;18:144-55.
  • Stefanski HE, Thibert KA, Pritchett J, Prusty BK, Wagner JE, Lund TC.  Fatal Myocarditis Associated with HHV-6 Following Immunosuppressoin in Two Children.  Pediatrics 2016;137:1-4.
  • Brunstein CG, Miller JS, McKenna DH, Hippen KL, DeFor TE, Sumstad D, Curtsinger J,  Verneris MR, MacMillan M, Levine BL, Riley J, June CH, Le C, Weisdorf D, McGlave PB, Blazar BR, Wagner JE.  Umbilical Cord Blood-Derived T Regulatory Cells to Prevent GVHD: Kinetics, Toxicity Profile and Clinical Effect.  Blood 2015 [First Edition, epub].

Randy Shaver Cancer Research and Community Funds 2016 awards announced

A total of $471,000 in funds were awarded sixteen cancer researchers at the Masonic Cancer Center, by the Randy Shaver Cancer Research and Community Funds 2016 grants.  Grants given are spent on technology and tools that enhance early detection of cancer, promising new programs that promote research that would help prevent cancer relapses, projects that demonstrate research in the area of cancer, and programs that enhance the lives of Minnesota’s cancer community by providing aid and assistance. The recipients and their projects are listed below:
  • Rehana Ahmed, M.D., Ph.D. and Janeen Trembley, Ph.D.: Investigation into targeting CK2 in melanoma ($25,000)
  • Martina Bazzaro, Ph.D.: Development of a test for predicting Paclitaxel response ($30,000)
  • Ran Blekhman, Ph.D.: Precision genomic approach for colon cancer characterization using the gut microbiome ($25,000)
  • Aaron LaBeau, Ph.D.: The development of a novel technology for the detection of prostate cancer      ($25,000)
  • Emil Lou, M.D., Ph.D.: Understanding how colon cancer cells communicate via tunneling nanotubes ($30,000)
  • Venkatram Mereddy, Ph.D.: Novel therapeutics for difficult to treat breast cancers ($25,000)
  • Branden Moriarity, Ph.D.: Pre-clinical testing of anti-SEMA4D antibody therapy for the treatment of pediatric osteosarcoma ($25,000)
  • Heather Nelson, Ph.D., M.P.H.: Genomic profiling for non-invasive screening of head and neck cancer ($26,000)
  • Michael Olin, Ph.D.: Immunotherapy for pediatric brain tumors ($34,000)
  • David Potter, M.D., Ph.D.: CYP3A4 mechanisms of breast cancer progression ($35,000)
  • Paolo Provenzano, Ph.D.: Combination stroma targeting therapy in pancreatic cancer ($30,000)
  • Tanya Pulver, M.D.: Developing a tool to predict outcome and guide clinical management of endometrial cancer ($25,000)
  • Patricia Scott, Ph.D.: Epigenetic regulation of the tumor suppressor gene KCNQ1 in colorectal cancer ($20,000)
  • Daniel Vallera, Ph.D.: Engaging the natural killer (NK) cells of our immune system to kill leukemia ($35,000). Vallera also received $25,000 for his work investigating drug development specific to pancreatic cancer.
  • Michael Verneris, M.D.: T cell exhaustion ($31,000)
  • Vaiva Vezys, Ph.D.: Therapeutic vaccination to control melanoma ($25,000)

Kudos
Congratulations to Erika Reith, a Pharmacology graduate student in the laboratory of Jill Siegfried, Ph.D., Cell Signaling Program, who recently was awarded a predoctoral fellowship in the T32 Pharmaco-neuroimmunology training grant.

12th Annual Women’s Health Research Conference issues call for abstracts
Masonic Cancer Center members are invited to submit a poster abstract on any topic related to women’s health or sex differences research to the Powell Center for Women’s Health, to be presented at the 12th Annual Women’s Health Research Conference on April 4, 2016 at the Campus Club in Coffman Union. Visit the website to submit an abstract.

This conference is co-sponsored by The Powell Center for Women’s Health, The Masonic Cancer Center, The Department of Medicine, and the Center for Child and Maternal Health in the School of Public Health.

Mini Medical School invites Masonic Cancer Center students to serve as hosts
This year’s Mini Medical School, “Breakthroughs in Cancer Research, Detection and Treatment” will be held every Monday in March and the first Monday in April. For the past several sessions, Mini Medical School has partnered with current health  sciences students who have served as the “hosts” each evening, introducing our speakers  and facilitating the Q&A portion of each class. Through this partnership with current  students, Mini Medical School attendees have gained some insight into what life is like for  medical students at the University of Minnesota and our student hosts have gained valuable  experience in speaking to large audiences (we average between 150 and 250 Mini Med  students) and the opportunity to network with some of the University’s most distinguished  faculty.  Student hosts are also welcome to attend any session of Mini Medical School free of charge. If interested, please contact the Mini Medical School staff at 612-624-4604 or colli588@umn.edu.

Center for Writing research grants
The Center for Writing's Interdisciplinary Studies of Writing (ISW) program offers research grants to support the inquiry of U of M scholars and teachers (faculty, P&A, and graduate students) into writing and literacy. Letters of intent are due Feb. 8.

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Program Meetings

BMT Program Meeting
Monday, February 1, 2016, 1:15-2:15 p.m., 450 MCRB
Importance of Conditioning Intensity and Remission in AML
Celalettin Ustun, M.D.

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Professional Education

February 1, 2016: Division of Health Policy and Management Faculty Candidate seminar
1:45-3 p.m., 2-120 Moos Tower
I’m Too Young for this! Opportunities for improving health outcomes for young adult cancer survivors
Helen Parsons, Ph.D., Assistant Professor, University of Texas Health Sciences Center, Adjunct Assistant Professor, University of Texas School of Public Health

View the web event.

February 2, 2016: The Association of Multicultural Scientists presents: Research and Development in Biotechnology
12-1 p.m., 1-125 CCRB
What is a Product Developer? How do I get there?
Joy Aho, Ph.D., Stem Cell Research and Development Manager at BioTechne

Lunch will be served. Please RSVP by January 28 to http://goo.gl/forms/y7R5gOjNmJ.

February 3, 2016: Cancer Biology Journal Club
12-1 p.m., 2-115 CCRB

Jamie Van Etten, Ph.D., Cancer Biology Training Grant postdoctoral fellow, Dehm lab, will discuss “The spliceosome is a therapeutic vulnerability in MYC-driven cancer,” T. Hsu TY et al., Nature 2015;525:384-388.

February 4, 2016: Epigenetics Consortium
3 p.m., room 105, 717 Delaware St. SE
Chemical biology approaches for inhibiting protein recognition of acetylated histones
Laura Hawk, Ph.D., postdoctoral associate, College of Science and Engineering, University of Minnesota

February 9, 2016: Tobacco Research Studies Meeting
2 p.m., room 105, 717 Delaware St. SE
Building tobacco research capacity in India: A critical resource for cancer prevention and
tobacco control efforts
Irina Stepanov, Ph.D., Assistant Professor, Division of Environmental Health Sciences
School of Public Health, University of Minnesota

Samir Khariwala, M.D., Associate Professor, Department of Otolaryngology, Head and Neck Surgery, University of Minnesota
We will discuss progress and challenges of our work on setting up a clinical site and analytical
laboratory in Mumbai. Currently, this resource is being used to investigate the relationship between tobacco carcinogen exposure and risk of oral cancer in India. Future biomarker‐based research opportunities utilizing this resource will also be discussed.

February 15, 2016: Advancing Your Research with CTSI Expertise – A special all-AHC faculty conversation
4-6 p.m., Mississippi Room, Coffman Memorial Union
Learn how the Clinical and Translational Science Institute (CTSI) is advancing and how CTSI's funding programs and expert resources can help bring your discoveries into practice. This informal event is for University researchers and will provide information on how best to use CTSI to advance your research projects and careers.

The event will include networking time, an informational program with a question and answer segment, and will conclude with expanded networking time to follow-up with presenters and connect with research colleagues.

The presentation portion of the event will be live streamed for faculty members outside the Twin Cities Metro area, and a recording will be available for those who cannot attend.

Hors d'oeuvres and refreshments will be served.  More information and registration details will soon be added to CTSI’s website. 

February 26, 2016: Forum on Ethical Issues in African Health Care
12-2 p.m., 2-101 NHH
This forum features three professionals conducting work and research in different regions of Africa and on very different aspects of health and health care. Each of them will talk about their work, with an emphasis on how ethics informs it and how their work derives new questions about what ethics means, for whom, and why. After discussion among the three, we encourage audience participation in continuing to debate the meaning of ethics, and how the many issues relating to health care across Africa push us to consider ethics in new ways. Visit the Center for Bioethics website for more information.

April 4, 2016: Save the date!: The 12th Annual Women’s Health Research Conference: Environmental Exposures and Hormones: Implications for Health
1-5 p.m., Coffman Theater, Coffman Memorial Union
Registration is now open.
Read more and submit an abstract.

April 25, 2016: Save the date! Minnesota HPV Vaccination Summit
The Masonic Cancer Center's Gynecologic Oncology Translational Working Group (Gyn Onc TWG) brings together cancer experts and healthcare leaders with one goal in mind: maximizing the success of research for the prevention and treatment of gynecologic cancers. Mark your calendar for Monday, April 25, 2016, for the Gyn Onc TWG's Minnesota HPV Vaccination Summit at the University of Minnesota.

Based on the same format as the national HPV vaccination summit held by the National Cancer Institute and Center for Disease Control last month at the MD Anderson Cancer Center in Houston, this day-long meeting will feature state and national HPV vaccination and cancer-prevention experts. We invite all of our interprofessional team of faculty and students, as well as partners from across Minnesota to actively participate in this historic cancer prevention summit. More information to follow.

May 9-10, 2016: 3rd Minnesota Neuro-Oncology Symposium
The mission of this Symposium is to educate researchers, clinicians, students, trainees, patients, caregivers, and community members on current and developing therapies for brain and nervous system tumors.

The Symposium with include two comprehensive programs designed to accommodate the specific interests of all those dedicated to finding a cure for brain tumors. The Research/Provider Program will present highly scientific content intended for researchers, physicians, students, and trainees. The Patient/Caregiver Program will present more practical information to patients, families, caregivers, and other community members with an interest in neuro-oncology. Visit the website.

May 9-10, 2016: Save the date!: Symposium on Germline Genetic Risk of Childhood Cancer: Where Do We Go From Here?
Organizers: Logan Spector, Ph.D., and Jenny Poynter, Ph.D.
Registration is free but attendance is limited to 100 persons.
Contact person:  Ginny Oie; email:  oie@umn.edu
More information will be available on the Department of Pediatric's Epidemiology and Clinical Research website.

May 18-20, 2016: Save the date!: Midwest Tumor Microenvironment Meeting
The Masonic Cancer Center is hosting the  Midwest Tumor Microenvironment Meeting May 18-20, 2016. The conference goal is to leverage the strength of tumor microenvironment researchers in the Midwest to re-engineer the tumor microenvironment to improve tumor therapy/normalize the tumor microenvironment. The agenda and registration/hotel information is coming soon! Read more.

June 30, 2016: Save the date!: John H. Kersey Lecture
Alan Ashworth, Ph.D., FRS
E. Dixon Heise Distinguished Professor in Oncology, University of California San Francisco
President, UCSF Helen Diller Family Comprehensive Cancer Center
Senior Vice President for Cancer Services, UCSF Health
Professor of Medicine, Division of Hematology/Oncology, Department of Medicine

November 2-3, 2016: Save the date!: 7th Annual Masonic Cancer Center Research Symposium
TCF Bank Stadium
The 7th Annual Masonic Cancer Center Research Symposium is being held in honor of Lee Wattenberg, M.D.

Keynote Speaker:
The 2016 B.J. Kennedy Lecturer in Medical Oncology
Thomas Kensler, Ph.D., Professor, Environmental Health Sciences, Bloomberg School of Public Health; Professor Department of Pharmacology and Molecular Sciences, Johns Hopkins School of Medicine; Professor of Pharmacology and Chemical Biology, University of Pittsburgh

Registration and schedule information will be available later in the year.

Visit the Education and Training Opportunities web page for more conference and special lecture listings.

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Events

February 20, 2016: Cancer and the Human Body
Science Museum of Minnesota, 120 W. Kellogg Blvd., St. Paul, MN

March 7-April 4, 2016: Mini-Medical School – Breakthroughs in Cancer Research and Treatment
Mondays, 6-8:30 p.m., for 5 weeks, Malcolm Moos Health Sciences Tower, Room 2-650, 515 Delaware St. SE, Minneapolis, MN 

Visit the website.
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April 23, 2016: SAVE THE DATE for the 11th Annual Cancer Survivorship Conference
Saturday, April 23, 2016, 8 a.m. - 1:30 p.m.
McNamara Alumni Center, University of Minnesota
A cancer diagnosis can alter the landscape of your life. Although it doesn't redefine you, it can change your lifetime health care needs. Save the date for this free educational conference that focuses on questions and issues survivors and their families often face after cancer treatment or following stem-cell transplantation.

Registration is required and will open in early 2016. To be added to the conference mailing list, please "click here".  

May 5-7, 2016: SAVE THE DATE! Promoting Health Equity Conference
Commons Hotel, Minneapolis
Details on the website.

May 9-10, 2016: 3rd Neuro-Oncology Program
The Patient/Caregiver Program will present more practical information to patients, families, caregivers, and other community members with an interest in neuro-oncology.

See more at http://www.peds.umn.edu/hematology-oncology/brain-tumor-program/symposium/index.htm

July 30, 2016: 2016 Marrow on the Move
Lake Nokomis, Minneapolis
Sponsored by the University of Minnesota Blood and Marrow Transplant Program
Contact: marrowonthemove@umn.edu, 612-625-8942.

Visit the Events and Community Outreach page for more information.

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Funding Announcements and Opportunities

Translational Product Development Fund opportunity
The Clinical and Translational Science Institute announces a funding opportunity for full-time faculty via Translational Product Development Fund (TPDF) request for applications. The TPDF will support health research projects that are intended to lead the development of a novel therapeutic device, diagnostic, or IT product, and will have the potential to be commercialized through the formation of a start-up company or license to an established commercial entity. Letters of intent are due by 5 p.m., Feb. 10.
Minnesota Futures Grant Program
Applications are now being accepted for the Minnesota Futures Grant Program, administered by the Office of the Vice President for Research. The Minnesota Futures program promotes new research and scholarship that address societal challenges by fostering opportunities for researchers to advance new ideas and cross disciplinary boundaries. Letters of Intent are due Feb. 22; full proposals are due March 21. Two grants will be awarded in June.

PAR-16-089
Imaging and Biomarkers for Early Detection of Aggressive Cancer (U01)
The purpose of this Funding Opportunity Announcement (FOA) is to: (i) invite researchers to submit collaborative research project (U01) applications to improve cancer screening, early detection of aggressive cancer, assessment of cancer risk and cancer diagnosis aimed at integrating multi-modality imaging strategies and multiplexed biomarker methodologies into a singular complementary approach, and (ii) establish a Consortium for Imaging and Biomarkers (CIB) to perform collaborative studies, exchange information, share knowledge and leverage common resources.
Funding: The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications. Application budgets are not limited but need to reflect the actual needs of the proposed project.
Key Dates:
Letter of Intent due June 11, 2016
Full application due July 11, 2016

PA-16-086
Supplements to Promote Clinical Research Studies on Pediatric Burkitt Lymphoma in Low- and Middle-Income Countries (Admin Support)
The Center for Global Health (CGH) at the National Cancer Institute (NCI) seeks to promote clinical research studies on pediatric Burkitt Lymphoma (BL) in low- and middle-income countries (LMICs) through collaborations and research partnerships between NCI-designated Cancer Centers and partner institutions in LMICs.
Funding: The combined direct cost budget for the 2-year project period may not exceed $200,000. Application budgets are limited to no more than $100,000 in direct costs in any single year.  These caps are exclusive of consortium/contractual Facilities and Administrative (F&A) costs.
Key Dates:
Application due April 15, 2016

Ovarian Cancer Investigator-Initiated Research Award
Supports meritorious basic and clinically oriented research in ovarian cancer. Impact is an important review criterion. Preliminary data are required. Clinical trials are not allowed. Pre-application is required, and then a full application is by invitation only.
Funding: Maximum funding of $450,000 in direct costs (plus indirect costs) over a period of performance of 3 years.
Key Dates:
Full announcement and application instructions will be posted on the Grants.gov website in February 2016.

PAR-16-084
Feasibility Studies to Build Collaborative Partnerships in Cancer Research (P20)
The National Cancer Institute (NCI) invites P20 planning grant applications for  developing collaborative partnership between institutions serving underserved health disparity populations and underrepresented students (ISUPS) and NCI- designated Cancer Centers (or Cancer Centers with highly integrated cancer research programs). This FOA is designed to facilitate the planning and execution of focused collaborations in cancer-related research, research experience, and research education. A major goal of the NCI P20 partnership programs is to provide support for investigators at ISUPS and Cancer Centers to conduct cancer research pilot projects and cancer research education program. The purpose of the pilot projects and education program is to allow awardees to obtain preliminary data that will lead to competitive grant applications for funding by the NIH/NCI and/or other Federal/Non-Federal agencies.
Funding: The combined budget of direct costs cannot exceed $275,000 over 4 years.
Key Dates:
Application due March 18, 2016

PAR-16-049
Small-Cell Lung Cancer (SCLC) Consortium: Therapeutic Development and Mechanisms of Resistance (U01)
This Funding Opportunity Announcement (FOA) invites applications to establish research teams of the Small-Cell Lung Cancer (SCLC) Consortium to conduct research whose overall goals are: 1) to improve SCLC therapeutics, focusing on understanding how the molecular vulnerabilities of this cancer could be used to develop targeted agent combinations; and/or, 2) to gain a better understanding of the rapid development of clinical resistance to drug and radiation therapy.
Funding: $450,000 Direct Costs (excluding consortium F&A costs) per year.
Key Dates:
Application due March 17, 2016

PA-14-151
Ruth L. Kirschstein National Research Service Award (NRSA) Individual Senior Fellowship (Parent F33)
The National Institutes of Health (NIH) awards senior individual research training fellowships to experienced scientists who wish to make major changes in the direction of their research careers or who wish to broaden their scientific background by acquiring new research capabilities as independent investigators in research fields relevant to the missions of participating NIH Institutes and Centers.
Funding: Individuals may receive up to 3 years of aggregate Kirschstein-NRSA support at the postdoctoral level, including any combination of support from institutional training grants (e.g., T32) and an individual fellowship award.
Key Dates:
Application due April 8, 2016

PA-16-086
Supplements to Promote Clinical Research Studies on Pediatric Burkitt Lymphoma in Low- and Middle-Income Countries (Admin Support)
The Center for Global Health (CGH) at the National Cancer Institute (NCI) seeks to promote clinical research studies on pediatric Burkitt Lymphoma (BL) in low- and middle-income countries (LMICs) through collaborations and research partnerships between NCI-designated Cancer Centers and partner institutions in LMICs.
Funding: The combined direct cost budget for the 2-year project period may not exceed $200,000. Application budgets are limited to no more than $100,000 in direct costs in any single year.  These caps are exclusive of consortium/contractual Facilities and Administrative (F&A) costs.
Key Dates:
Application due April 15, 2016

PAR-16-089
Imaging and Biomarkers for Early Detection of Aggressive Cancer (U01)
The purpose of this Funding Opportunity Announcement (FOA) is to: (i) invite researchers to submit collaborative research project (U01) applications to improve cancer screening, early detection of aggressive cancer, assessment of cancer risk and cancer diagnosis aimed at integrating multi-modality imaging strategies and multiplexed biomarker methodologies into a singular complementary approach, and (ii) establish a Consortium for Imaging and Biomarkers (CIB) to perform collaborative studies, exchange information, share knowledge and leverage common resources.
Funding: The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications. Application budgets are not limited but need to reflect the actual needs of the proposed project.
Key Dates:
Letter of Intent due June 11, 2016
Full application due July 11, 2016 

Minnesota Futures Grant Program
In keeping with the OVPR’s strategic plan to address societal challenges, the MN Futures Grant Program is designed to promote research and scholarship beyond existing initiatives through fostering opportunities for researchers to cross disciplinary and professional boundaries. The program is designed to promote in-depth work to enable faculty members to respond collaboratively and boldly to emerging opportunities in interdisciplinary research and scholarship.
Key Dates:
Letter of Intent due February 22, 2016
Full application due March 21, 2016

DoD Breast Cancer Research Program
The Fiscal Year 2016 Defense Appropriations Act provides $120 million to the Department of Defense Breast Cancer Research Program (BCRP) to support innovative, high-impact breast cancer research to accelerate progress toward ending breast cancer.
Funding: Varies
Submission due date TBA in February 2016

Visit the Funding Opportunities Web page to see listings previously published in Update. A list of organizations that provide funding for cancer research is also provided there.

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Employment Opportunities

Researcher 2: Breast Cancer
A Researcher position is available with Dr. Julie Ostrander to work on projects related to the role of proto-oncogenes and their downstream signaling pathways in breast cancer initiation and progression, and the development of compounds to sensitize cancer cells to chemotherapy. Processes such as cell proliferation, survival, and metastasis along with genome expression analyses are examined in cell and animal models as well as patient tissues. Candidates should have a B.A. or B.S. degree in biology, chemistry or related science discipline and 1 year experience.  This is a temporary position expected to last up to one year. Interested individuals should go to the Employment System to search and apply for the following job opening: 306821 (Researcher 2: Breast Cancer). 

Researcher 2: Comparative Oncology
A Researcher 2 position is open in the laboratory of Dr. Jaime Modiano working on comparative oncology. A Bachelor (BS or BA) and/or a Masters (MS or MA) degree in life sciences (Biology, Immunology, Genetics, Biochemistry, or equivalent) or Basic Sciences (Chemistry or equivalent) and prior laboratory experience (>1 year) are required, including mastery of tissue culture and sterile techniques and especially handling hematopoietic cells and cancer cells. Highly desirable skills include proficiency in contemporary cellular, molecular, and biochemical techniques, including, but not limited to fundamental knowledge of methods in flow cytometry, isolation of proteins and nucleic acids, cell culture, PCR, RT-PCR, immunoblotting, cloning, transfection/transduction, sequencing, immunoprecipitation, immunofluorescence, microscopy, and digital imaging. Documented training in handling and working with laboratory mice is also desirable, particularly first aid and techniques such as tumor injection, adoptive transfer of cells, anesthesia, live imaging, and necropsy.

Prior experience (>6 months) in a laboratory with a fundamental understanding of purchasing systems and experience communicating with vendors and other company representatives, supervising graduate and/or undergraduate students, scheduling and coordination of laboratory meetings, and overseeing laboratory safety. Demonstrated capability in directing the technical aspects of a research project is preferred.

Qualified applicants should apply at the University of Minnesota Online Employment website at www.umn.edu/ohr/employment and use 307060 in the keyword search function.

Postdoctoral Positions in Cancer Bioengineering and Cancer Biology
Motivated postdoctoral associates are sought to join the Engineering in Oncology Laboratory of Dr. Paolo Provenzano at the University of Minnesota in Minneapolis, MN. Our laboratory studies the physical and molecular mechanisms driving cancer progression to metastasis and resistance to therapeutic intervention, and develops therapeutic strategies to re-engineer the tumor microenvironment.

A Ph.D. in the field of Biomedical Engineering, Biophysics, Cell Biology, Immunology, or a related field and a demonstrated (with 1st author publications) track record of productive research experience is required. See our ad in Nature for more information on the require qualifications. To apply please write to provenzanolab@gmail.com with the subject line:
Cancer Bioengineering/Biology Postdoctoral Position. Please include an up to date CV, 1-2 relevant publications in PDF format, and a brief description of your research interests and relevant background as related to our research program and your near term and long term goals. Letters of reference may be requested at a later date.

Postdoctoral Associate
A postdoctoral associate position is available in the lab of Ran Blekhman (http://blekhmanlab.org). The lab uses genomics and computational approaches to study the mechanism of host-microbiome interactions and their role in colorectal cancer. The ideal candidate would be highly motivated to conduct independent research, and hold a PhD in genetics, bioinformatics, computer science, statistics, microbiology, or a related field, with a solid publication record. Candidates should have a strong analytical background, have experience with analysis of next-generation sequence data, and proficiency with computer and statistical programing languages. The successful candidates will enjoy a competitive salary and benefits package. Interested candidates are encouraged to contact Ran Blekhman by email (blekhman@umn.edu), and provide a brief cover letter detailing research experience and interests, a CV, and contact information for three references. Informal enquires are welcome. Applications will be accepted starting immediately and until the positions are filled.

Postdoctoral Associate
Dr. Bruce Walcheck, Immunology Program, is seeking a highly motivated individual for an NIH-funded postdoctoral position in leukocyte biology in inflammation and cancer. The Walcheck lab’s research is focused on the cell and molecular biology of leukocytes in the context of inflammation and the host response to cancer. Ectodomain shedding by specific membrane-associated proteases occurs in the microenvironment of the cell membrane of leukocytes and regulates the surface density of numerous receptors and the release of cell stimulatory factors. This process is central to the regulation of diverse leukocyte effector
functions, including their infiltration of tissue sites and killing of target cells. A better understanding of this proteolytic process may provide novel therapies for cancer and diseases resulting from excessive inflammation.

Interested applicants should email their CV and a cover letter with a statement of research interests to: walch003@umn.edu.

Postdoctoral Associate
Dr. Yoji Shimizu, Immunology Program leader, is recruiting a postdoctoral associate to investigate the mechanisms of action of novel mouse models of focal and scaffold-based
tumor immunotherapies. Applications from investigators with a recent or expected Ph.D. in biomedical sciences are encouraged. The ideal candidate will have demonstrated experience with laboratory mice and mouse cancer models, proficiency with flow cytometry, excellent oral and written communication skills, and an interest in developing independent research aims. Contact Dr. Yoji Shimizu (shimi002@umn.edu) or Dr. Brandon Burbach (burba005@umn.edu).

Postdoctoral Scholar
Two postdoctoral positions are available in the lab of Ben Hackel for a funded project on protein engineering of novel targeting ligands using an innovative combinatorial library approach. The lab, in the Department of Chemical Engineering and Materials Science, applies protein engineering technologies to develop in vivo molecular targeting agents for molecular imaging and targeted therapy, with a focus on oncology. We balance (1) fundamental study of molecular evolution and protein biophysics, which empowers our protein engineering efforts; (2) fundamental study of physiological transport of protein ligands, which guides improved delivery of molecular imaging agents and therapies; and (3) application of advances in these aims towards clinical challenges in disease detection and treatment. The current openings fall at the interface of (1) and (3). We seek motivated researchers with a Ph.D. in any related discipline as we value the diverse perspectives and expertise of an interdisciplinary environment. Experience in molecular biology and protein chemistry are beneficial. A demonstrated record of scientific achievement, including publications and presentations, is essential. A successful candidate will demonstrate strong work ethic, creativity, and productivity. Please send a brief description of your career goals, your curriculum vitae, and contact information for three references to hackel@umn.edu.  

Web Developer, Oncology Medical Informatics Services
A Web Developer position is available to work with project and business teams to understand business requirements and analysis plans associated with data initiatives, to design the right solution and consult on best practices and code reviews, and to participate as a team member and assist other team members as needed.   Oncology Medical Informatics & Services (OMIS) provides technology and data mining support to its customers who include principal investigators and their teams, the Clinical Trials Office, Translational Cell Therapy Lab and individual cancer center members. We manage patient registries such as the outcomes registry for the BMT Program. The OMIS team also supports the center's administrative office by providing metrics and clinical trial accrual data to comply with the National Cancer Institute's Cancer Center Support Grant guidelines.  Interested individuals should go to the Employment System to search and apply for the following job opening: 307114 (Web Developer).

Clinical Data Associate II, Clinical Trials Office
The Masonic Cancer Center Clinical Trials Office (CTO) is currently recruiting a Clinical Data Associate. The primary purpose of the Clinical Data Associate (CDA II) position is to conduct research subject registration and yearly follow-up for the University of Minnesota’s Blood and Marrow Transplant Database and for the Center for International Blood and Marrow Transplant Research (CIBMTR) as part of reporting requirements.  A bachelor’s degree in a health-related field and 2 years of experience in a medical or scientific field or a combination of related education and work experience to equal 6 years is required.  Qualified candidates will have experience with blood or marrow transplants including terminology, obtaining Authorization of Release of medical information, medical data abstraction, EMR systems and experience working in a research setting.  Interested individuals should go to the Employment System to search and apply for the following job opening: 306820 (Clinical Data Associate II). 

Operations Manager, Clinical Trials Office
The Masonic Cancer Center Clinical Trials Office (CTO) is currently recruiting an Operations Manager to partner with the CTO Director to increase the efficient use of resources, streamline the start-up phase of all oncology clinical trials, maintain and manage the budget and ensure ongoing and up-to-date staff training. This position will also manage and lead Project Management personnel which will require facilitating successful interactions with key functional groups which include Clinical Teams, Data Management, MHealth, FRA, UMP, CTSI, Financial Hub, PIs, Quality Assurance.  The qualified candidate will have a bachelor’s degree and 8 years’ experience in medical research to include project management of clinical trials, supervisory experience and clinical research certification.  Interested individuals should go to the Employment System to search and apply for the following job opening: 306822 (CTO Operations Manager). 

Clinical Research Nurse Coordinators – Solid Tumor
The Masonic Cancer Center Clinical Trials Office is currently recruiting Clinical Research Nurse Coordinators for solid tumor interventional trials. Clinical trials include Phase I-II trials under locally held INDs, as well as Phase II/III industry sponsored trials. The Clinical Research Nurse coordinates all aspects of a portfolio of clinical trials including patient management and safety, protocol administration, and educating and training research staff, clinical staff, medical providers, patients and their families. Conducts, coordinates and serves as a resource for various aspects of clinical trials from start-up to closeout according to study protocols. Interested individuals should go to the Employment System to search and apply for the following job openings: 305776 (Research Nurse) and 305715 (Senior Clinical Research Nurse).

Principal Office and Administrative Specialist
Working in the Masonic Cancer Center’s administrative office, the Principal Office and Administrative Specialist provides general office support including reception, conference room management, expense reimbursements and reconciliation, etc.; and specific support for operations and human resources.   This position requires advanced proficiency in Microsoft Office and electronic calendaring and with forms, tables and databases. Interested individuals should go to the Employment System to search and apply for the following job opening: 306546 (Prin Ofc & Admin Specialist).

Oncology Clinical Trials Data Management Analyst
The Oncology Clinical Trials Data Management Analyst performs data management and applies data quality techniques to improve the usability of systems and data. This position will act as the liaison between Masonic Cancer Center business users, OMIS team and the Clinical trials office to manage the oncology Clinical Trials Management System.  A bachelor’s degree in a related field and at least 2 years progressively responsible experience is required.  The selected candidate will have experience with system and process validation and documentation; in protocol review, case report form development; in abstracting data from electronic case report forms and electronic study calendars; in managing clinical trial data and creating data management plan; in training individuals and groups; and a demonstrated understanding of oncology medical terminology and considerable knowledge of blood and marrow transplant.  Interested individuals should go to the Employment System to search and apply for the following job opening: 306143 (Oncology Clinical Trials Data Management Analyst).

Functional Genomics of GI Tract Cancers Discover Team Recruitment
The University of Minnesota Medical School, in collaboration with the Masonic Cancer Center, is focusing efforts to hire outstanding physicians, researchers, and bioinformaticists for a Discovery Team to work on functional genomics of gastrointestinal (GI) tract cancers. This new team will build off current research, leverage the teams and shared resources already in place, as well as bring their own research interests to develop new technologies and models for understanding tumor heterogeneity.

We are seeking a dynamic mid-career or senior physician scientist with training in pathology or medical oncology to lead this effort and are conducting a national search to find the right person. The successful candidate will be expected to assume the leadership role for existing faculty and future hires, and expand a comprehensive program in GI cancer spanning basic science, translational genomics, and clinical trials. The successful candidate will be appointed with tenure in the Department of Medicine’s Division of Hematology, Oncology and Transplantation or the Department of Laboratory Pathology. Visit the job posting (#301436) for more information.

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  • Last modified on February 5, 2016