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Researchers and Staff
November 20 , 2007
Cancer Center Update is sent to Cancer Center members and staff every Tuesday at 10 a.m. Please submit items to Sandi Sherman, sherm019@umn.edu, by noon the previous Friday.
In This Issue
Cancer Center Program Meetings
Funding News and Opportunities
Today's Cancer Center Seminar
Tuesday, November 20, 2007, 12-1 p.m., 450 CCRB
Promoting cervical health on the Apsa'alooke reservation: A community-based participatory research project
Susanne Christopher, Ph.D., Professor, Community Health, Montana State University, Bozeman
and
Eleanor Pretty On Top, Board Member, Messengers for Health
Host: Jean Forster, Ph.D., M.P.H.
A peek at next week's seminar:
Tuesday, November 27, 2007, 12-1 p.m., 450 CCRB
Cellular control of Rb/E2F induced proliferation and apoptosis in cancer
Timothy C. Hallstrom, Ph.D., Assistant Professor, Department of Pediatrics, Division of Hematology, Oncology, Blood and Marrow Transplantation, University of Minnesota
Visit the Cancer Center Seminar Series calendar for a complete schedule of lectures.
News
Members in the news
Joe Neglia, M.D., Prevention and Etiology Program member, was quoted in the November issue of Minnesota Medicine in an article about the decision-making challenges cancer patients confront when weighing treatment options. Read more.
Cancer Center researchers to present at annual AACR Frontiers in Cancer Prevention Research conference
Irina Stepanov, Ph.D., Hecht lab, will present a poster "Detection and quantitation of N'-nitrosonornicotine in human toenails by liquid chromatography-electrospray ionization-tandem mass spectrometry" at the Biomarkers of Carcinogen Exposure session during the annual AACR Frontiers in Cancer Prevention Research conference. For a complete list of presenters visit our Web site.
Cancer Center researchers to present at ASH meeting
Several Cancer Center researchers and University of Minnesota colleagues will be among the presenters at the American Society of Hematology (ASH) meeting in Atlanta, December 8-12, 2007. If you or someone from your laboratory is giving an oral or poster presentation at ASH, and you have not been listed yet, please e-mail Gina Kennedy, kenne069@umn.edu, to be included on the list and in a future edition of Update.
Oral Presentations:
Rachel Bergerson, graduate student, Largaespada lab, "Novel Mll-AF9 cooperating genes identified in a leukemogenesis screen using retroviral mutagenesis"
Maki Shindo, M.D., Ph.D., Chen lab, Pediatric BMT, "Acute myeloid leukemias: Therapy excluding transplantation-immunotherapeutic approaches"
Jakub Tolar, M.D., Ph.D., Assistant Professor, Pediatric H/O/BMT, "Induction of skin repair mechanism by bone marrow derived SLAM family receptor enriched cells in murine epidermolysis bullosa"
Michael Verneris, M.D., Assistant Professor, Pediatric H/O/BMT, "Umbilical cord blood T cells express the natural cytotoxicity receptors, NKp30, NKp44 and Nkp46 after IL-15 ttimulation, but only NKp30 is functional"
Poster presentations:
Bartsoz Grzywacz, M.D., Verneris lab, "Stromal cells support a myeloid pathway of human NK cell differentiation"
Wei Chen, M.D., Ph.D., Associate Professor, Pediatric BMT, "The indoleamine 2,3-dioxygenase pathway is essential for human plasmacytoid dendritic cell-induced adaptive T regulatory cell generation"
Ashish Kumar, M.D., Ph.D., Assistant Professor, Pediatric H/O/BMT, "Acute myeloid leukemia: Biology and pathophysiology"
Cary Martinez, M.D., Pediatric BMT Fellow, "GD2+ selected mesenchymal stromal cells demonstrate a more robust proliferation and differentiation potential compared to unselected cells"
Jakub Tolar, M.D., Ph.D., Assistant Professor, Pediatric H/O/BMT, "Dyskeratosis congenita: Low regimen-related toxicity following hematopoietic cell transplantation using a reduced intensity conditioning regimen" and "Glycosaminoglycans as anticoagulants in mucopolysaccharidosis Type I (MPS I)"
Bin Yin, Ph.D., Largaespada lab, "Bcl11a causes p21Cip1 down-regulation and transplantable leukemia in Nf1-deficient mice"
K. Scott Baker, M.D., Associate Professor, Pediatric H/O/BMT, "Clinical results: Alternative donor transplantation-matched unrelated donors and haploidentical transplants"
Jakub Tolar, M.D., Ph.D., Assistant Professor, Pediatric H/O/BMT, "Brain sparing conditioning regimen and umbilical cord blood transplantation for inherited high risk neurologic metabolic diseases"
Leukemia & Lymphoma Society issues "Call for Nominations" for 2nd Annual Relentless for a Cure Award
The 2nd Annual Relentless for a Cure Award will be presented at The Leukemia & Lymphoma Society's 2008 Man & Woman of the Year Grand Finale Gala in June. The award is given to an outstanding Minnesota medical professional whose research, diagnosis and/or treatment has contributed to improved quality of life for patients and their families and/or great advancements in the field of lymphoma or blood cancers. The professional can be a physician or a researcher who is actively practicing or retired.
The deadline for nominations is January 11, 2008. Read a pdf with complete information on how to make a nomination.
Education and Events
Lab Medicine and Pathology Grand Rounds
Wednesday, November 21, 2007, 8-9 a.m., Eustis Amphitheater, D-230 Mayo
Cell polarity: A novel regulatory step for cancer initiation and progression
Senthil Muthuswamy, Ph.D., Associate Professor, Cold Spring Harbor Laboratory
Wine and cheese reception for Paul Marker and Lara Collier
Wednesday, November 21, 2007, 3-4 p.m., 6-135 Jackson
Cancer Center members and staff are invited to a farewell reception for Paul and Lara, who are departing to the University of Wisconsin.
Cancer Center Staff and Faculty Recognition Program
Wednesday, November 28, 2007, 2 p.m., 450 CCRB
Cancer Center faculty and staff are invited to the quarterly Recognition Program. This event will focus on activities and research in Population Sciences. A recognition award will be presented to an individual or group for their outstanding contribution to the Masonic Cancer Center's mission. Refreshments will be served.
Special Seminar
Friday, November 30, 2007, 11:30 a.m.-12:30 p.m., 450 CCRB
Primary prevention of cardiovascular disease: Detecting and treating endothelial activation in children
Aaron Kelly, Ph.D. Assistant Professor, Department of Pediatrics, University of Minnesota
Dr. Kelly is a candidate for assistant/associate professor (tenure-track) in Pediatric Epidemiology and Clinical Research. For questions, contact Ginny Oie, 626-2902.
Cancer Center Program Meetings
BMT Conference
Monday, November 26, 2007, 1:15-2:15 p.m., 450 CCRB
Research Updates: ASH oral presentations
Activating KIR (B haplotype) in unrelated donors improves disease-free survival after HLA-matched and mismatched allogeneic transplantation for acute myeloid leukemia: Implications for donor selection using KIR genotyping
Sarah Cooley, M.D., Hematology, Oncology and Transplantation
STAT5A overexpression enhances killer immunoglobulin receptor (KIR) expression in developing NK cells and is associated with a loss of reverse transcription from the proximal KIR promoter
Frank Cichocki, Miller lab
For a complete schedule, visit the Web site.
Genetic Mechanisms of Cancer Program Seminar
Thursday, November 29, 2007, 4-5 p.m., 3-110 Moos Tower
A forward genetic screen for gastrointestinal tract cancer genes
Tim Starr, Ph.D. Postdoctoral Associate, Largaespada lab
For a complete schedule, visit the Web site.
Funding News and Opportunities
Brain Tumor Society Research Grant Program
Application Deadlines: Letter of intent form due January 16, 2008. Invited full proposals due April 16, 2008.
Funding: 1-2 year, $100,000/yr direct costs. No indirect allowed.
The Brain Tumor Society seeks letters of intent for scientific research on brain tumors directed at finding a cure. Any project with the potential to advance basic scientific and translational brain tumor research will be considered. Clinical projects will not be funded. Funds may be used for startup projects or supplementary funding.
Visit the Funding News & Opportunities Web page to see listings previously published in Update.