Masonic Cancer Center

A comprehensive cancer center designated by the National Cancer Institute

MCC Update 09-24-13

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Update is an official newsletter of the Masonic Cancer Center for faculty, members, staff, colleagues, and friends. All submissions for the next issue must be sent to Sandi Sherman,, by noon on Friday for publication the following Tuesday.


September 24, 2013


In This Issue

Cancer Center Seminar


Professional Education


Funding Opportunities

Cancer Center Seminar

Note new location!

Tuesday, September 24, 2013, 1-125 Cancer and Cardiovascular Research Building (Seminar will be videocast in 450 MCRB)
Taxane chemotherapy targets the androgen receptor: The armageddon of prostate cancer
Natasha Krypniou, M.D., Chair, Department of Urology, University of Kentucky

Host: Mohammad Saleem, Ph.D.

A peek at next week’s seminar
The Bumps and Sweat devices: Two fast, sensitive measures of CIPN
William R. Kennedy, M.D., M.S., Professor of Neurology, University of Minnesota

Host: Anne Blaes, M.D.

Visit the calendar for a schedule of seminars.

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Members in the news

Todd Tuttle, M.D., Cancer Detection, Treatment and Survivorship Program, was quoted in a Fox News story about a study published in the Annals of Internal Medicine showing that women with breast cancer may overestimate their secondary risks.

Aasma Shaukat, M.D., was interviewed in an MPR story about a study she led showing a common test can cut the risk of dying from colorectal cancer by as much as a third over three decades.

Douglas Yee, M.D., Masonic Cancer Center director and a University of Minnesota Physicians breast cancer specialist, appeared on Fox 9 last week to discuss a new drug that combats breast cancer in its earliest stages. Read more.


Congratulations to David Rothenberger, M.D., who will assume the role of head of the Department of Surgery October 1. He succeeds Selwyn Vickers, M.D., who is returning to the University of Alabama to become Senior Vice President for Medicine and Dean of the UAB School of Medicine. Read more.

Kudos to Ashok Saluja, Ph.D., Cell Signaling Program, who was awarded the prestigious George Palade Medal at the Joint Meeting of the International Association of Pancreatology and the Korean Pancreatobiliary Association.

Members receive grants

Logan Spector, Ph.D., Prevention and Etiology Program, is the recipient of a two-year $250,000 grant from Hyundai Hope on Wheels to study the genetic causes of osteosarcoma in children. The grant will be used to examine the protein-coding portions of the genomes (known as exomes) of about 100 osteosarcoma patients and their parents. By comparing patients' exomes to their parents' new mutations will be located. Genes where these mutations cluster will be considered very likely to be involved in causing osteosarcoma. Knowing the genetic causes of osteosarcoma may suggest new therapies and screening strategies to catch tumors earlier and improve patient outcomes.

David Largaespada, Ph.D., Jaime Modiano, V.M.D., Ph.D., Subree Subramanian, Ph.D., and Logan Spector, Ph.D., received a two-year $499,833 grant from the Zach Sobiech Osteosarcoma Fund for his project “Germline and somatic genetic determinants in osteosarcoma outcomes.”

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Professional Education

September 25, 3013: Cancer Biology Journal Club
12-1 p.m., 6-101 NHH
Britnie James will be discussing  “Accessory cells of the microenvironment protect multiple myeloma from T cell cytotoxicity through cell adhesion-mediated immune resistance,” de Harrt SJ et al., Clin Cancer Res 2013.

September 26-27, 2013: The Second Minnesota Neuro-Oncology Symposium: Basic Discovery Accelerating Groundbreaking Brain Tumor Therapy
McNamara Alumni Center, 200 Oak Street SE, Minneapolis, Minn.
Presented by: The Brain Tumor Program, Masonic Cancer Center, University of Minnesota, University of Minnesota Medical Center, Fairview, University of Minnesota Amplatz Children’s Hospital

For more information and to register visit the website.

September 26, 2013: Cancer Care Service Line Dinner and Workshop
5:30-8 p.m., McNamara Alumni Center, Maroon and Gold Room
This event is a great way to meet colleagues and make connections across the campus and community clinics, while providing input on important service line initiatives.
Agenda includes:

  • Update from Bobbi Daniels, MD and Carolyn Wilson
  • Summary of service line performance, key initiatives and strategic planning
  • Discussion session: The future of cancer care
    • Continuing progress towards a multidisciplinary practice by disease teams regardless of clinic location
    • Redesigning care coordination - changing roles and responsibilities
    • Implementing new care models

Register on the website.

September 30, 2013: Save the date: Cancer Care Physician Dinner and Workshop
5:30-8 p.m.
Details to follow in August.

September 27, 2013: Department of Surgery Special Lecture
4 p.m., 11-157 PWB
Understanding and Treating Cancer: A Historical Perspective over Two Millenia
Dr. Alan Chapman, Faculty of History, University of Oxford

This lecture is cosponsored by the Program in the History of Medicine.

October 8, 2013: Specialized Centers of Research on Sex Differences (SCOR) Seminar
10 a.m., 450 MCRB
Individual differences in response to nicotine and vulnerability to nicotine addiction
Neal Benowitz, M.D., Professor, Medicine and Bioengineering & Therapeutic Sciences, Chief, Division of Clinical Pharmacology, University of California San Francisco

Light refreshments will be provided. Questions, call 612-624-0896.

October 7-9, 2013: Point of Care Technologies for Cancer
NIH campus, Bethesda, MD
Co-sponsored by National Cancer Institute (NCI) and the National Institute of Biomedical Imaging and Bioengineering (NIBIB), the main goal of the conference is to facilitate new scientific collaborations and interactions among cancer researchers and bioengineers, and to build new research programs in this important field in order to promote the translation of new technologies into clinical applications. The talks will address various aspects of cancer and discuss new cutting-edge point of care technologies with potential for cancer detection, diagnosis and treatment. For more information and to register visit

For conference related questions please contact Amanda Fleming (  301-228-4491

October 9, 2013: The Minnesota Chemoprevention Consortium
12-3 p.m., Hormel Foods Corporation, 2 Hormel Place, Austin, Minn.

If you have a proposal or data that you would like to present/discuss,  please contact Steve Hecht at

Lunch will be provided. RSVP to  if you plan to attend and indicate if you would like a vegetarian lunch.

October 16, 2013: 4th Annual Masonic Cancer Center Research Symposium
10:30 a.m. to 4:30 p.m., Great Hall, Coffman Memorial Union
The Masonic Cancer Center Science Council announces its Fourth Annual Research Symposium October 16, 2013 in the Great Hall of Coffman Memorial Union from 10:30 a.m. to 3:30 p.m. The symposium will include a presentation by Douglas Yee, M.D., director of the Masonic Cancer Center, and two poster session periods.

Keynote speaker:
Carl June, M.D.,
B.J. Kennedy Lecturer in Medical Oncology
Richard W. Vague Professor in Immunotherapy
Smilow Center for Translational Research
Perelman School of Medicine
University of Pennsylvania

"Engineering CARs for cancer: lessons from Detroit"

For more information visit the website.

October 28, 2013: Department of Radiology Grand Rounds
5 p.m., Center for Magnetic Resonance Imaging, 2nd floor conference room
Innovation in Breast MRI
Don Plewes, M.D., University of Toronto

New clinical developments in Breast MRI-where will we be in 5 years?
Steve Harms, M.D., Mana Medical Associates

November 6, 2013: Mouse Necropsy Workshop
9-11:30 a.m., Room 495, Animal Science/Veterinary Medicine
This workshop will be led by CPSR board certified veterinary pathologists, Drs. Johnson, Kovi and O’Sullivan.  It is designed for individuals who are doing in vivo studies in mice with endpoints necessitating necropsy and collection of tissues, and is appropriate for principal investigators, postdocs, graduate students and technicians.  Participants will learn how to necropsy mice and identify and collect tissues of interest.  Issues related to optimum handling and fixation of tissues will be emphasized.  The registration fee is $100. Places are limited and reserved on a first come-first served basis.  To reserve a place please email

Contact Josh Parker at 612 625 9770, with questions.

November 20, 2013: Save the Date: Poster Session & Awards Banquet
4-7 p.m., Amherst H. Wilder Foundation, 451 Lexington Pkwy N, St. Paul, Minn. Poster session at 4:00; banquet at 5:30
The Program in Health Disparities Research (PHDR), Clinical and Translational Science Institute (CTSI), and Center for Health Equity (CHE) will hold their 2013 Poster Session and Awards Banquet where research presentations from the PHDR Pilot Grants in Health Disparities Research program, CTSI Collaborative Pilot Grant awardees, and research poster presentations from CHE/CTSI Scholars will be given. This poster session will also feature pilot grant awardees and the work of local community organizations dedicated to reducing health disparities.

Visit the Education and Training Opportunities web page for more conference and special lecture listings.

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May 17, 2013: Save the Date: Cancer Survivorship Series
Click here to be added to the Cancer Survivor Program mailing list to receive registration information for this conference when it is available closer to the date.

Visit the Community Events and Outreach page for more information.

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Funding Opportunities

American Cancer Society Institutional Research Grant
Deadline: November 1, 2013
Funding: $30,000
This grant is for assistant professors who have no independent national funding and are engaged in cancer-related research. Cancer-related research includes cancer etiology, mechanisms of carcinogenesis and chemoprevention, molecular mechanisms of cancer progression and metastasis, development of novel cancer therapeutic or chemoprevention models and translational research, cancer immunology and immunotherapy.

This is a one-year seed grant. Funding is available up to $30,000. Applications may be obtained by emailing a request to . For information, please call Aaron Schilz, 612-624-0650.

2013 Masonic Cancer Center Internal Grants Program
Masonic Cancer Center, University of Minnesota
Required Statement of Intent:  Friday, September 20, 2013
Application Deadline:  November 1, 2013
Funding:  see table below

Six internal grant mechanisms are available through the Masonic Cancer Center.  Finding and award info is summarized in the table below.  The goal of these programs is to foster the development of and provide support for novel research ideas that focus on a problem in cancer. In turn, the Masonic Cancer Center expects that internal funding will lead to nationally peer reviewed funding. 

Brainstorm Award



Cancer Detection, Treatment and Survivorship Award



Cancer Prevention & Control Award



Hematologic Malignancy Innovations Award



Minnesota Chemoprevention Consortium (MC^2) Award



Translational Breast Cancer Research Award



A link to the required Statement of Intent and details regarding each mechanism is here.

If you have questions, please contact Aaron Schilz, Research Grant Coordinator at the Masonic Cancer Center (; 612-624-0650).

TTR Core Usage Funding Program
Sponsor: Office of Discovery and Translation - CTSI
Application Deadline (ongoing): 5 p.m. on the 10th day of any month
Funding: up to $10,000 to use a TTR-designated Core Resource for up to one year
The Core Usage Funding Program is designed to support clinical or translational projects. Basic research projects are ineligible. The supported studies may be either pilot projects, intended to generate preliminary data for larger studies, or projects nearing the final stages of completion but now require additional data the Core Resources can generate. It is expected that a Core Usage grant will be used to generate data to support an external grant submission or patent application.

Visit the Funding Opportunities Web page to see listings previously published in Update. A list of organizations that provide funding for cancer research is also provided there.

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  • Last modified on September 30, 2013