MCC Update 09-10-13
Update is an official newsletter of the Masonic Cancer Center for faculty, members, staff, colleagues, and friends. All submissions for the next issue must be sent to Sandi Sherman, email@example.com, by noon on Friday for publication the following Tuesday.
September 10, 2013
Note the new location!
Tuesday, September 10, 2013, 1-125 Cancer and Cardiovascular Research Building (Seminar will be videocast in 450 MCRB)
Exceptionally potent tubulysins for antibody-drug conjugates
Robert Fecik, Ph.D., Associate Professor, Department of Medicinal Chemistry, University of Minnesota
A peek at next week’s seminar
Transposon mutagenesis and gene targeting for understanding sarcoma initiation, promotion, and progression
David Largaespada, Ph.D., American Cancer Society Research Professor, Department of Genetics, Cell Biology and Development, Department of Pediatrics, Associate Director for Basic Science, Masonic Cancer Center
Visit the calendar for a schedule of seminars.
Members in the news
As part of the Minnesota high school football “Tackle Cancer” campaign to raise money for cancer research, Kare11-TV ran a story about the research of the late John Ohlfest, Ph.D., member of the Masonic Cancer Center’s Immunology Program. The story featured interviews with David Largaespada, Ph.D., Genetic Mechanisms of Cancer Program and the Masonic Cancer Center Associate Director of Basic Science, Michael Olin, Ph.D., and John Wagner, M.D., co-leader of the Transplant Biology and Therapy Program. View the video.
Edward Greeno, M.D., Cancer Detection, Treatment and Survivorship Program and director of the University of Minnesota Medical Center Fairview’s Oncology Service Line, was quoted in a Health Talk story about a phase 1 clinical trial to assess the toxicity of minnelide, a drug developed at the University of Minnesota to treat pancreatic cancer.
Melissa Geller, M.D., Transplant Biology and Therapy Program, was interviewed in a story about ovarian cancer on KSTP-TV during the “Silent No More Walk/Run” sponsored by the Minnesota Ovarian Cancer Alliance. View the video.
Congratulations to Masato Yamamoto, M.D., Ph.D., Genetic Mechanisms of Cancer Program, who was invited to be a member of the AACR Pancreatic Cancer Research Grants Scientific Review Committee, which reviews Pancreatic Cancer Action Network-AACR career development and fellowship awards and pancreatic research grants.
Kudos to Gunda George, Ph.D., Cell Signaling Program member, on her induction into the AHC Academy for Excellence in Health Research. This is the highest recognition of excellence in research by AHC faculty of those who have enhanced the research identity of the University of Minnesota through sustained nationally- and internationally-recognized biomedical or health-related research in their field.
Members speak at conferences
Masato Yamamoto, M.D., Ph.D., Genetic Mechanisms of Cancer Program, chaired a symposium on “Gene & Vector-based Molecular Imaging” at the Japanese Society of Gene Therapy Annual meeting in Okayama in July. He also presented his research on “Novel theranostic for imaging and treatment of pancreatic cancer.”
Clinical Assay Development Program Call for Applications
The NCI Clinical Assay Development Program (CADP) is accepting applications from investigators seeking clinical assay development and validation resources. These resources are designed to assist with the development of assays that may predict therapy response or prognostic behavior of a diagnosed cancer, primarily for use in clinical trials. In addition to access to the Institute’s assay and validation resources, approved projects will receive project management support. The application deadline is October 15, 2013.
The following clinical trials conducted by Masonic Cancer Center members were recently opened:
A Phase I, Multicenter, Open-label, Dose-Escalation, Safety, Pharmacokinetic and Pharmacodynamic Study of Minnelide given daily for 21 days followed by 7 days off schedule in patients with Advanced GI Tumors
PI: Greeno, Edward
For more information on clinical trials contact Marva Bohen, R.N., B.S.N. (firstname.lastname@example.org, 612-624-2620).
September 11, 2013: Cancer Biology Research Club
12-1 p.m., 6-101 NHH
Pro-apoptotic Noxa regulates metabolism in leukemia
Eric Hanse, Cancer Biology Training Grant predoctoral fellow, Kelekar lab
Visit the calendar for a schedule of meetings.
September 12, 2013: Comparative Oncology Seminar
12-1 p.m., 280 VDL (St. Paul campus)
Immunophenotypic features of bortezomib-resistant myeloma cells - utilization of a murine model to develop a human diagnostic test
Michael Linden, M.D., Ph.D., Assistant Professor, Department of Laboratory Medicine and Pathology
Pizza will be served.
September 16, 2013: 10th Annual Women’s Health Research Conference – “Optimizing Women’s Health Through a Life Course Approach”
McNamara Alumni Center, 200 Oak St, Minneapolis, Minn.
Paula Braveman, M.D., M.P.H., Professor, Family and Community Medicine, University of California-San Francisco
Janet Rich-Edwards, ScD, M.P.H., Investigator, Nurses’ Health Study, Harvard School of Public Health
To register visit the website.
September 26-27, 2013: The Second Minnesota Neuro-Oncology Symposium: Basic Discovery Accelerating Groundbreaking Brain Tumor Therapy
McNamara Alumni Center, 200 Oak Street SE, Minneapolis, Minn.
Presented by: The Brain Tumor Program, Masonic Cancer Center, University of Minnesota, University of Minnesota Medical Center, Fairview, University of Minnesota Amplatz Children’s Hospital
For more information visit the website.
September 26, 2013: Cancer Care Service Line Dinner and Workshop
5:30-8 p.m., McNamara Alumni Center, Maroon and Gold Room
This event is a great way to meet colleagues and make connections across the campus and community clinics, while providing input on important service line initiatives.
- Update from Bobbi Daniels, MD and Carolyn Wilson
- Summary of service line performance, key initiatives and strategic planning
- Discussion session: The future of cancer care
- Continuing progress towards a multidisciplinary practice by disease teams regardless of clinic location
- Redesigning care coordination - changing roles and responsibilities
- Implementing new care models
September 30, 2013: Save the date: Cancer Care Physician Dinner and Workshop
Details to follow in August.
October 16, 2013: 4th Annual Masonic Cancer Center Research Symposium
10:30 a.m. to 4:30 p.m., Great Hall, Coffman Memorial Union
The Masonic Cancer Center Science Council announces its Fourth Annual Research Symposium October 16, 2013 in the Great Hall of Coffman Memorial Union from 10:30 a.m. to 3:30 p.m. The symposium will include a presentation by Douglas Yee, M.D., director of the Masonic Cancer Center, and two poster session periods.
Carl June, M.D.,
B.J. Kennedy Lecturer in Medical Oncology
Richard W. Vague Professor in Immunotherapy
Smilow Center for Translational Research
Perelman School of Medicine
University of Pennsylvania
For more information visit the website.
October 28, 2013: Department of Radiology Grand Rounds
5 p.m., Center for Magnetic Resonance Imaging, 2nd floor conference room
Innovation in Breast MRI
Don Plewes, M.D., University of Toronto
New clinical developments in Breast MRI-where will we be in 5 years?
Steve Harms, M.D., Mana Medical Associates
November 20, 2013: Save the Date: Poster Session & Awards Banquet
4-7 p.m., Amherst H. Wilder Foundation, 451 Lexington Pkwy N, St. Paul, Minn. Poster session at 4:00; banquet at 5:30
The Program in Health Disparities Research (PHDR), Clinical and Translational Science Institute (CTSI), and Center for Health Equity (CHE) will hold their 2013 Poster Session and Awards Banquet where research presentations from the PHDR Pilot Grants in Health Disparities Research program, CTSI Collaborative Pilot Grant awardees, and research poster presentations from CHE/CTSI Scholars will be given. This poster session will also feature pilot grant awardees and the work of local community organizations dedicated to reducing health disparities.
Visit the Education and Training Opportunities web page for more conference and special lecture listings.
September 15, 2013: Pancreatic Cancer Action Network PurpleRide
8 a.m., Elm Creek Regional Park, 12400 James Deane Parkway, Maple Grove, Minn. 55369
Please join us in the fight against Pancreatic Cancer! The University of Minnesota Team "U" Can Make Difference will be riding on Sunday September 15th, 2013 for the Annual PurpleRide event sponsored by the Pancreatic Cancer Action Network. This is a fun-filled family event and will consist of an 8 and 25 mile bike ride with all proceeds going toward the Pancreatic Cancer Action Network for pancreatic cancer research. Joining our team is easy! If interested please visit the website at www.purpleride.org and click on team: "U" Can Make a Difference." Can't make it that day and/or want more information? Donate online or buy one of our t-shirts to show your support by contacting Sheila Bohnsack at email@example.com or 612-625-7936. Hope to see you there!
September 18, 2013: Varsity Team Rally
6-9 p.m., Cancer and Cardiovascular Research Building, U of M Biomedical District
Drive cancer research down the field at this unique, insider’s special event. Help us raise $100,000 for high-priority cancer research projects at Masonic Cancer Center, University of Minnesota.
For more information and to register, visit www.drivecancerresearch.org.
Visit the Community Events and Outreach page for more information.
2013 Masonic Cancer Center Internal Grants Program
Masonic Cancer Center, University of Minnesota
Required Statement of Intent: Friday, September 20, 2013
Application Deadline: November 1, 2013
Funding: see table below
Six internal grant mechanisms are available through the Masonic Cancer Center. Finding and award info is summarized in the table below. The goal of these programs is to foster the development of and provide support for novel research ideas that focus on a problem in cancer. In turn, the Masonic Cancer Center expects that internal funding will lead to nationally peer reviewed funding.
Cancer Detection, Treatment and Survivorship Award
Cancer Prevention & Control Award
Hematologic Malignancy Innovations Award
Minnesota Chemoprevention Consortium (MC^2) Award
Translational Breast Cancer Research Award
A link to the required Statement of Intent and details regarding each mechanism is here.
If you have questions, please contact Aaron Schilz, Research Grant Coordinator at the Masonic Cancer Center (firstname.lastname@example.org; 612-624-0650).
2013 Kay Yow/V Foundation Award – Women, Aging and Cancer
Jimmy V Foundation for Cancer Research
Deadline: September 20, 2013
Funding: $500,000 - $1,000,000 over 4 years
A one page description of the concept and a draft budget in NIH format should be emailed to Aaron Schilz, email@example.com by 4:30 pm September 20th. The concept and budget will be reviewed by a director appointed committee if there is more than one application. The Kay Yow Cancer Fund is interested in funding a translational research project focused on the area of cancers in aging women. The project must include a clinical trial endpoint. Corss-institutional and cross-disciplinary efforts are encouraged. The grant will be awarded in February 2014 with payment beginning late Spring 2014.
TTR Core Usage Funding Program
Sponsor: Office of Discovery and Translation - CTSI
Application Deadline (ongoing): 5 p.m. on the 10th day of any month
Funding: up to $10,000 to use a TTR-designated Core Resource for up to one year
The Core Usage Funding Program is designed to support clinical or translational projects. Basic research projects are ineligible. The supported studies may be either pilot projects, intended to generate preliminary data for larger studies, or projects nearing the final stages of completion but now require additional data the Core Resources can generate. It is expected that a Core Usage grant will be used to generate data to support an external grant submission or patent application.
Visit the Funding Opportunities Web page to see listings previously published in Update. A list of organizations that provide funding for cancer research is also provided there.