Masonic Cancer Center

A comprehensive cancer center designated by the National Cancer Institute

MCC Update 04-30-13

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April 30, 2013

 

In This Issue

Cancer Center Seminar

News

Clinical Trials

Program Meetings

Professional Education

Events

Funding Opportunities

Position Available


Cancer Center Seminar

April 30, 2013, 12-1 p.m., 450 MCRB
Electrical properties imaging of biological tissues and applications to cancer detection
Bin He, Ph.D., Professor, Department of Biomedical Engineering, Director, Institute for Engineering in Medicine, Director, Center for Neuroimaging

Next seminar:

No May 7 seminar due to speaker cancellation.

The next seminar will be:

May 14, 2013, 12-1 p.m., 450 MCRB
Prostate Cancer Update: PSA screening, imaging and active surveillance
Christopher Warlick, M.D., Ph.D., Assistant Professor, Department of Urologic Surgery, University of Minnesota

View the Cancer Center Seminar calendar for a complete schedule and to watch recorded seminars.

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News  

Members in the news

John Wagner, M.D., and Michael Verneris, M.D., Transplant Biology and Therapy Program, were interviewed in numerous media outlets about their groundbreaking treatment to cure boy of HIV and leukemia. Coverage appeared in Storify, Star Tribune, Fox News, WCCO-TV, KARE-11 TV, KMSP-TV, KSTP-TV, KTTC-TV, Rochester Post-Bulletin, KAAL-TV, KSTC-TV, MPR’s The Daily Circuit and Health Talk.

University of Minnesota biomedical engineering professor David Odde, Ph.D., Tumor Microenvironment Program, and Theatre, Arts and Dance Department Chair Carl Flink started collaborating four years ago after attending a workshop on finding chaos in different disciplines. Read more in the Minnesota Daily.

The study on prophylactic mastectomy led by Todd Tuttle, M.D., Cancer Outcomes and Survivorship Program, that was described in the Journal of Clinical Oncology, was mentioned in a New York Times Magazine story about breast cancer screening and over-diagnosis. Tuttle was also quoted in the article. Read more.

Jayanth Panyam, Ph.D., Carcinogenesis and Chemoprevention Program, discussed the risk to graduate training posed by the sequester cuts. Read more in the Minnesota Daily.

Brenda Weigel, M.D., was mentioned in a Duluth News Tribune story about the treatment of a Hermantown man battling a rare cancer.

Kudos
Congratulations to the University of Minnesota Medical Center, Fairview’s Palliative Care Program on recently receiving the Advanced Certification for Palliative Care by The Joint Commission. This certification recognizes hospital palliative care programs who have undergone a rigorous review of clinical and operational standards, demonstrate expertise in interdisciplinary palliative care, and achieve quality benchmarks. Less than 40 hospitals across the country have achieved this certification.

Gyn Onc Translational Working Group encourages attendance at annual meeting on women’s cancer
The Gyn Onc Translational Working Group is offering support to non-Gyn Onc faculty, including those basic scientists working with OB/GYN, whose abstracts are accepted for the Annual Meeting on Women’s Cancer. All areas of research related to gynecologic oncology are encouraged to submit abstracts. Based on the number of abstracts accepted for oral presentations, the Gyn Onc TWG will provide funds to cover part of the cost for individuals to attend the conference. The goal is to encourage translational research partners from the University to submit abstracts and attend. If you, would like further information prior to submitting, please contact Dr. Melissa Geller (6244-8420) or Matt Gerber (624-9486). Information on abstract submission is available on the website.

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Clinical Trials

The following clinical trials conducted by Masonic Cancer Center members were recently opened: 

2013CG015
COG AHOD1221: A Phase 1/2 Study of Brentuximab Vedotin (SGN35, IND# 117117) in Combination with Gemcitabine for Pediatric and Young Adult Patients with Relapsed or Refractory Hodgkin Lymphoma
PI: Weigel, Brenda

For more information on clinical trials contact Marva Bohen, R.N., B.S.N. (ccinfo@umn.edu,  612-624-2620).

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Program Meetings

BMT Program Meeting
Monday, May 6, 2013, 1:15-2:15 p.m., 450 MCRB
Adult Outpatient Care Model Update: Brainstorm session to expand care needed for our growing patient population
Erica Warlick, M.D.

Visit the calendar for a schedule of meetings.

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Professional Education

April 24, 2013: Cancer Biology Journal Club
12-1 p.m., 6-101 NHH
Brian Andersen, Neuroscience graduate student in the Largaespada lab, will discuss “Anti-CTLA-4 Antibodies of IgG2a Isotype Enhance Antitumor Activity through Reduction of Intratumoral Regulatory T Cells,” Selby MJ et al., Cancer Immunology Research 2013; (OnLine First.)

May 21, 2013: 6th Annual Biomedical Sciences Research Recognition Day
10:30 a.m.-4 p.m., Coffman Union Great Hall
Keynote speaker: Mario Capecchi, Ph.D., 2007 Nobel Prize Laureate, Investigator, Howard Hughes Medical Institute, University of Utah School of Medicine
“Gene targeting into the 21st century: Mouse models of human disease from cancer to neuropsychiatric disorders”

Graduate student poster session from 6 Biomedical Sciences Programs will be on display. Lunch and refreshments is provided. Registration is required for this free event. Register by May 10 at http://orbs.umn.edu/gradresearchday/

May 23, 2013: Chemical Biology Interface Training Grant Symposium
8:30 a.m.-4:30 p.m., MCB 3-120
This is a day-long event designed to highlight research at the interface of chemistry and biology and to facilitate discussion between graduate students and distinguished researchers. A complete schedule can be found on the symposium website: http://www.chem.umn.edu/bio/Symposium2013/index.html.

Graduate students and post docs in the chemical and biological sciences are additionally invited to participate in the midday poster session by submitting a poster title and abstract. Please register by May 13th using this form. Registration includes lunch and light snacks, as well as ample opportunity to interact with our speakers.

Questions may be addressed to chemcbit@umn.edu.
The symposium will feature scientists from academia and industry speaking on their research at the intersection of chemistry, biology and medicine.

June 19-20, 2013: Cancer Disparities Summit: Moving Communities Towards Change
Sponsors: Minnesota Center for Cancer Collaborations (MC3) and Minnesota Cancer Alliance
The Cancer Disparities Summit will provide participants with a chance to learn about disparities that exist in cancer screening, treatment and mortality, to educate participants about how they can improve cancer prevention, management and survivorship, and to understand how they can participate in initiatives aimed at reducing the cancer disparities throughout Minnesota. One and a half day meeting in Twin Cities with plenary speakers and break-out workshops, poster session, possibly with an evening reception. For more information visit the website.

Registration is now open online.

Visit the Education and Training Opportunities web page for more conference and special lecture listings.

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Events 

June 2, 2013: Growing Through the Narrow Spots
5-7 p.m., Indoor Club, TCF Bank Stadium, 420 23rd Avenue SE, Minneapolis, Minn.
Special Guest Host: James Denton
June 2, National Cancer Survivors Day, is also the launch date for Ruth Bachman's new book, Growing Through the Narrow Spots." Please join Ruth Bachman and James Denton for this fun and inspirational evening. This will be the first annual event in the Twin Cities in honor of "National Cancer Survivors Day" - a celebration of survivors, their families and support networks.The evening will include musical and meaningful entertainment accompanied by wine and appetizers.

Attendees will receive a complimentary copy of the book. Proceeds raised from the event will benefit a number of worthy organizations whose missions fund cancer research, education, and advocacy.

Ticket Price: $50/person.

For more information: mruth@ruthbachman.com; 612-770-1010

June 22, 2013: Time to Fly 2013
Harriet Island Regional Park, St. Paul, Minn.
The Children's Cancer Research Fund's athletic fundraising event includes a 10K and 5K run, a 5K walk and a kids' fun run. Visit http://www.childrenscancer.org/timetofly/ for more information and to register.

September 18, 2013: Save the Date for Varsity Team Rally III!
6-9 p.m., Cancer/Cardiovascular Building, Biomedical Discovery District

Visit the Community Events and Outreach page for more information.

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Funding Opportunities 

Program Project Development Grant
Sponsor: Ovarian Cancer Research Fund
Deadline(s): Letter of Intent due May 23, 2013.
Funding: $300,000/yr for three years.

Liz Tilberis Early Career Award
Sponsor:
Ovarian Cancer Research Fund
Deadline(s): Letter of Intent due May 23, 2013.
Funding: $150,000/yr for three years

Ann Schreiber Mentored Investigator Award
Sponso
r: Ovarian Cancer Research Fund
Deadline(s): Letter of Intent due May 23, 2013.
Funding: $75,000

Request for Application (RFA): CTSI KL2 Scholars Program (RFA-5)
Sponsor: CTSI
Deadline:
June 26, 2013, 12 Noon.
The KL2 Scholars Program is available to Assistant Professors (in rank 6 years), conducting clinical or translational research. The program provides 75% salary support (up to $100,000 inclusive of fringe), $25,000 in research funds, and $1,000 travel funds a year, for 3 years. It requires a primary, secondary and biostatistician faculty mentoring team. It includes weekly multidisciplinary seminars with BIRCWH (Women's Health K12) and CHRCDA (Child Health K12) programs, CTSI Pre-K Scholars, and Individual K awardees. Up to five proposals will be awarded on this RFA.

Please note – an initial biostatistical consultation, at no charge, with a BDAC biostatistician to review statistical support needs for the proposal is required. Contact the CTSI Research Navigator at 612-626-2318 or ctsi@umn.edu to request an appointment. It is recommended you schedule this meeting at the beginning of the application process to avoid delays due to availability.

Visit the Funding News & Opportunities web page to see listings previously published in Update. A list of organizations that provide funding for cancer research is also available there.

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Position Available

A postdoctoral position is immediately available for NIH-funded projects that will investigate the functional interactions between DNA replication machinery and DNA repair pathways for genome stability and tumor suppression using mouse models. In particular, the Shima Lab is interested in elucidating the mechanism responsible for the activation of dormant replication origins. For more information, please see our papers listed below. 

Kawabata et al., (2011) Stalled fork rescue via dormant replication origins in unchallenged S phase promotes proper chromosome segregation and tumor suppression. Mol Cell 41:543-553.

Shima et al. (2007) A viable allele of Mcm4 causes chromosome instability and mammary adenocarcinomas in mice, Nature Genetics 39: 93-98.

We are looking for a highly motivated individual with a recent PhD or MD/PhD. A candidate must have a strong background in molecular biology/genetics and is expected to work at the bench independently. To apply, please send your curriculum vitae, a brief description of your career goal, and the names and addresses of 3 references to shima023@umn.edu.

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  • Last modified on May 6, 2013